room 1016, building U3, tel. +39 02 6448 3052

lab 5040, building U4, tel. +39 02 6448 3514

veronica.krenn@unimib.it

see also: ResearcherID (publons), ORCID, Linkedin,  Twitter, Scopus

Cascio Anna – Postgraduate Fellow
lab 5040, building U4, tel. +39 02 6448 3514
anna.cascio@unimib.it

Veronica Krenn graduated cum Laude in Biotechnologies at the University of Milano-Bicocca, Italy, and received a PhD in Molecular Medicine at the University of Milano, with an internship at the Institute of Experimental Oncology (IEO), working on human mitotic division in the Musacchio laboratory.

She moved to the Max-Planck Insitute of Molecular Physiology in Germany during her PhD and later to the Knoblich laboratory at the Vienna BioCenter as Post-Doc, where she started to work on human brain organoid systems. She joined our department in 2022, after being awarded with the Early Career Fellowship promoted by the Human Technopole.

Brain development, cerebral organoids, iPSCs, microglia, neuroinflammation, genetic diseases, congenital infections

Health

Genetic Diseases, Neurodegenerative and neurological diseases, Stem cells and Regenerative Medicine

The lab uses stem cells - derived models to investigate the molecular basis of neuroimmune interactions regulating brain development and their alterations in disease conditions

Human Neuroimmunobiology Project - The project aims at developing human stem cells- derived 2D and 3D cellular models to study the mechanisms of neuroimmunological dysfunction and their contribution to the pathogenesis of neurodevelopmental disorders.

-Krenn, V., Bosone, C., Burkard, T.R., Spanier, J., Kalinke, U., Calistri, A., Salata, C., Rilo Christoff, R., Pestana Garcez, P., Mirazimi, A., Knoblich, J.A. 2021 Organoid modeling of Zika and herpes simplex virus 1 infections reveals virus-specific responses leading to microcephaly. Cell Stem Cell 28, 1362–1379.e7. doi:10.1016/j.stem.2021.03.004

-Bajaj, S., Bagley, J.A., Sommer, C., Vertesy, A., Nagumo Wong, S., Krenn, V., Lévi-Strauss, J., Knoblich, J.A., 2021. Neurotransmitter signaling regulates distinct phases of multimodal human interneuron migration. EMBO J. 40, e108714. doi:10.15252/embj.2021108714

National collaborations:

Prof. Silvia Nicolis, Università degli Studi di Milano-Bicocca (UNIMIB)

Prof. Giuseppe Testa, Human Technopole

International collaborations:

Prof. Jürgen Knoblich, IMBA -Vienna

Dr. Christopher Esk, University of Innsbruck

Krenn’s Lab – #KrennLab_BtBs
last update June 2022