Krenn Veronica
Collaborator - Human Technopole Early Career Fellow
room 1016, building U3, tel. +39 02 6448 3052
lab 5040, building U4, tel. +39 02 6448 3514
see also: ResearcherID (publons), ORCID, Linkedin, Twitter, Scopus
Research Group
Cascio Anna – Postgraduate Fellow
lab 5040, building U4, tel. +39 02 6448 3514
anna.cascio@unimib.it
Background
Veronica Krenn graduated cum Laude in Biotechnologies at the University of Milano-Bicocca, Italy, and received a PhD in Molecular Medicine at the University of Milano, with an internship at the Institute of Experimental Oncology (IEO), working on human mitotic division in the Musacchio laboratory.
She moved to the Max-Planck Insitute of Molecular Physiology in Germany during her PhD and later to the Knoblich laboratory at the Vienna BioCenter as Post-Doc, where she started to work on human brain organoid systems. She joined our department in 2022, after being awarded with the Early Career Fellowship promoted by the Human Technopole.
Keywords
Brain development, cerebral organoids, iPSCs, microglia, neuroinflammation, genetic diseases, congenital infections
Research interest
The lab uses stem cells - derived models to investigate the molecular basis of neuroimmune interactions regulating brain development and their alterations in disease conditions
Research projects
-A human organoid-based culture of Central nervous system-Associated Macrophages (CAM) for functional study of -neurodevelopment and disease
Anno: 2023
Bando: FAQC 2023 - prima finestra
Enti finanziatori: Università degli Studi di MILANO-BICOCCA
-Human Neuroimmunobiology Project - The project aims at developing human stem cells- derived 2D and 3D cellular models to study the mechanisms of neuroimmunological dysfunction and their contribution to the pathogenesis of neurodevelopmental disorders.
Anno: 2021
Enti finanziatori: FONDAZIONE HUMAN TECHNOPOLE
Selected articles
-Krenn, V., Bosone, C., Burkard, T.R., Spanier, J., Kalinke, U., Calistri, A., Salata, C., Rilo Christoff, R., Pestana Garcez, P., Mirazimi, A., Knoblich, J.A. 2021 Organoid modeling of Zika and herpes simplex virus 1 infections reveals virus-specific responses leading to microcephaly. Cell Stem Cell 28, 1362–1379.e7. doi:10.1016/j.stem.2021.03.004
-Bajaj, S., Bagley, J.A., Sommer, C., Vertesy, A., Nagumo Wong, S., Krenn, V., Lévi-Strauss, J., Knoblich, J.A., 2021. Neurotransmitter signaling regulates distinct phases of multimodal human interneuron migration. EMBO J. 40, e108714. doi:10.15252/embj.2021108714
International and national collaborations
National collaborations:
Prof. Silvia Nicolis, Università degli Studi di Milano-Bicocca (UNIMIB)
Prof. Giuseppe Testa, Human Technopole
International collaborations:
Prof. Jürgen Knoblich, IMBA -Vienna
Dr. Christopher Esk, University of Innsbruck
Krenn’s Lab – #KrennLab_BtBs
last update June 2022