Serra Immacolata, PhD

Assistant Professor of Chemistry and Biotechnology of Fermentations

FOTO sito BtBs Serra Immacolata

room 4023, building U4

room 4054, building U4, tel. +39 02 6448 3428

see also: Scopus Author ID: 22942087500, Loop


Microbial Biotechnology; Biorefinery; Enzymes; Residual biomasses; Biocatalysis; Metabolic engineering

The activity is focused on the following research lines

industrial biotechnology research area BtBs UNIMIB
Industrial Biotechnology

Metabolic engineering, Process and product, Synthetic Biology

Enviromental Biodiversity and Ecosystem Reasearch area BtBs UNIMIB
Enviromental Biodiversity and Ecosystem

Microbial Diversity and Bioprospecting

Research interest

The main research interests are:

- Exploitation of microbial biodiversity for the production of chemicals, biofuels and enzymes. In particular, one research line concerns the up-cycling of residual biomasses by microbial bioprocesses for the production, for instance, of single cell oils and lactic acid.  Dr. Serra research activity has dealt also with the characterization of osmotic stress in marine yeasts and in S. cerevisiae by flow cytometry techniques, the identification of enzymatic activities of biocatalytic interest in marine yeasts and the optimization of growth conditions of marine yeasts in order to maximize the expression of the enzymes of interest.

- Biotransformations catalyzed both by isolated enzymes (soluble and immobilized) and by whole cells. Identification, cloning, heterologous expression, characterization and immobilization of enzymes for biocatalytic purposes and their use in batch and flow systems.

Selected articles

-Di Lorenzo R.D., Serra I., Porro D., Branduardi P. State of the art on the microbial production of industrially relevant organic acids (2022) Catalysts, 12 (2), art. no. 234.

-Donzella, S., Serra, I., Fumagalli, A., Pellegrino, L., Mosconi, G., Lo Scalzo, R., et al. Recycling industrial food wastes for lipid production by oleaginous yeasts Rhodosporidiobolus azoricus and Cutaneotrichosporon oleaginosum (2022) Biotechnology for Biofuels and Bioproducts, 15(1). DOI: 10.1186/s13068-022-02149-3

-Robescu M.S., Serra I.,* Terreni M., Ubiali D.,* Bavaro T. A multi-enzymatic cascade reaction for the synthesis of vidarabine 5'-monophosphate (2020) Catalysts, 10 (1), art. no. 60.

-Serra I., Guidi B., Burgaud G., Contente M.L., Ferraboschi P., Pinto A., Compagno C., Molinari F., Romano D. Seawater-based biocatalytic strategy: stereoselective reductions of ketones with marine yeasts (2016) ChemCatChem, 8 (20), pp. 3254-3260.

Serra’s Lab – #SerraLab_BtBs
last update: June