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Lodola Francesco, PhD

Associate Professor of Physiology

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Francesco Lodola BtBs UNIMIB

room 3014, building U3, tel. +39 02 6448 3228

lab 3015, building U3, tel. +39 02 6448 3331

lab 3050, building U3, tel. +39 02 6448 3316

francesco.lodola@unimib.it

see also: ResearchGate, Google Scholar, Scopus, ResearchID, ORCID, loop

Research Group

Chiara Florindi, PhD Student (XXXVIII Ciclo)
Lab 3015 (tel. +39 6448 3331), building U3
Lab 3050 (tel. +39 6448 3316), building U3
c.florindi@campus.unimib.it

Francesca Misitano, PhD Student (XXXIX Ciclo)
Lab 3015 (tel. +39 6448 3331), building U3
Lab 3050 (tel. +39 6448 3316), building U3
f.misitano@campus.unimib.it

Ludovica Cestariolo, Assegnista  
Lab 3015 (tel. +39 6448 3331), building U3
Lab 3050 (tel. +39 6448 3316), building U3
ludovica.cestariolo@unimib.it

The activity is focused on the following research lines

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Health research area BtBs UNIMIB
Health

Cardiovascular disease, Drug Discovery and Pharmacology, Nanomedicine and biomaterials

Keywords

Cardiovascular Physiology, Ca2+ signaling, Excitation-contraction coupling, Arrhythmias, Optical stimulation, Nanomaterials, Nanomedicine. 

Research interest

Ca2+ signaling and cardiac arrhythmias; Novel optics-based approaches for cardiac electrophysiology.

Research projects

1.    Non genetic light stimulation for the treatment of cardiac arrhythmias
2.    Interaction between myofilament and SERCA2a activators on heart muscle mechanics

Selected articles

*Co-first author, #Corresponding author

[1] C. Maniezzi, M. Eskandr, C. Florindi, M. Ferrandi, P. Barassi, E. Sacco, V. Pasquale, A.S. Maione, G. Pompilio, V.O.N. Teixeira, R.A. de Boer, H.H.W. Silljé, F. Lodola#, A. Zaza, Early consequences of the phospholamban mutation PLN‐R14del+/− in a transgenic mouse model, Acta Physiologica (2024). DOI: 10.1111/apha.14082

[2] V. Vurro, B. Federici, C. Ronchi, Florindi C., V. Sesti, S. Crasto, Maniezzi C., Galli C., M.R. Antognazza, C. Bertarelli, E.D. Pasquale, Lanzani G., F. Lodola#, Optical modulation of excitation-contraction coupling in human induced pluripotent stem cell-derived cardiomyocytes, iScience (2023). DOI: 10.1016/j.isci.2023.106121

[3] M.L. DiFrancesco, F. Lodola*, E. Colombo, L. Maragliano, M. Bramini, G.M. Paternò, P. Baldelli, M.D. Serra, L. Lunelli, M. Marchioretto, G. Grasselli, S. Cimò, L. Colella, D. Fazzi, F. Ortica, V. Vurro, C.G. Eleftheriou, D. Shmal, J.F. Maya-Vetencourt, C. Bertarelli, G. Lanzani, F. Benfenati, Neuronal firing modulation by a membrane-targeted photoswitch, Nature Nanotechnology (2020). DOI: 10.1038/s41565-019-0632-6

[4] F. Lodola#, V. Vurro, S. Crasto, E. Di Pasquale, G. Lanzani Optical Pacing of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Mediated by a Conjugated Polymer Interface. Advanced Healthcare Materials (2019). DOI: 10.1002/adhm.201900198

International and national collaborations

Prof. Guglielmo Lanzani and Dr. Maria Rosa Antognazza - Istituto Italiano di Tecnologia

Prof. Kevin Kit Parker - Harvard University

Prof.ssa Chiara Bertarelli and Prof. José Félix Rodriguez Matas - Politecnico di Milano

Prof. Giulio Pompilio - Centro Cardiologico Monzino

Prof.ssa Cecilia Ferrantini - Università di Firenze


Lodola’s Lab – #LodolaLab_BtBs
last update: March 2024