Lodola Francesco, PhD
Associate Professor of Physiology
room 3014, building U3, tel. +39 02 6448 3228
lab 3015, building U3, tel. +39 02 6448 3331
lab 3050, building U3, tel. +39 02 6448 3316
see also: ResearchGate, Google Scholar, Scopus, ResearchID, ORCID, loop
Research Group
Chiara Florindi, PhD Student (XXXVIII Ciclo)
Lab 3015 (tel. +39 6448 3331), building U3
Lab 3050 (tel. +39 6448 3316), building U3
c.florindi@campus.unimib.it
Francesca Misitano, PhD Student (XXXIX Ciclo)
Lab 3015 (tel. +39 6448 3331), building U3
Lab 3050 (tel. +39 6448 3316), building U3
f.misitano@campus.unimib.it
Ludovica Cestariolo, Assegnista
Lab 3015 (tel. +39 6448 3331), building U3
Lab 3050 (tel. +39 6448 3316), building U3
ludovica.cestariolo@unimib.it
The activity is focused on the following research lines
Health
Cardiovascular disease, Drug Discovery and Pharmacology, Nanomedicine and biomaterials
Keywords
Cardiovascular Physiology, Ca2+ signaling, Excitation-contraction coupling, Arrhythmias, Optical stimulation, Nanomaterials, Nanomedicine.
Research interest
Ca2+ signaling and cardiac arrhythmias; Novel optics-based approaches for cardiac electrophysiology.
Research projects
1. Non genetic light stimulation for the treatment of cardiac arrhythmias
2. Interaction between myofilament and SERCA2a activators on heart muscle mechanics
Selected articles
*Co-first author, #Corresponding author
[1] C. Maniezzi, M. Eskandr, C. Florindi, M. Ferrandi, P. Barassi, E. Sacco, V. Pasquale, A.S. Maione, G. Pompilio, V.O.N. Teixeira, R.A. de Boer, H.H.W. Silljé, F. Lodola#, A. Zaza, Early consequences of the phospholamban mutation PLN‐R14del+/− in a transgenic mouse model, Acta Physiologica (2024). DOI: 10.1111/apha.14082
[2] V. Vurro, B. Federici, C. Ronchi, Florindi C., V. Sesti, S. Crasto, Maniezzi C., Galli C., M.R. Antognazza, C. Bertarelli, E.D. Pasquale, Lanzani G., F. Lodola#, Optical modulation of excitation-contraction coupling in human induced pluripotent stem cell-derived cardiomyocytes, iScience (2023). DOI: 10.1016/j.isci.2023.106121
[3] M.L. DiFrancesco, F. Lodola*, E. Colombo, L. Maragliano, M. Bramini, G.M. Paternò, P. Baldelli, M.D. Serra, L. Lunelli, M. Marchioretto, G. Grasselli, S. Cimò, L. Colella, D. Fazzi, F. Ortica, V. Vurro, C.G. Eleftheriou, D. Shmal, J.F. Maya-Vetencourt, C. Bertarelli, G. Lanzani, F. Benfenati, Neuronal firing modulation by a membrane-targeted photoswitch, Nature Nanotechnology (2020). DOI: 10.1038/s41565-019-0632-6
[4] F. Lodola#, V. Vurro, S. Crasto, E. Di Pasquale, G. Lanzani Optical Pacing of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Mediated by a Conjugated Polymer Interface. Advanced Healthcare Materials (2019). DOI: 10.1002/adhm.201900198
International and national collaborations
Prof. Guglielmo Lanzani and Dr. Maria Rosa Antognazza - Istituto Italiano di Tecnologia
Prof. Kevin Kit Parker - Harvard University
Prof.ssa Chiara Bertarelli and Prof. José Félix Rodriguez Matas - Politecnico di Milano
Prof. Giulio Pompilio - Centro Cardiologico Monzino
Prof.ssa Cecilia Ferrantini - Università di Firenze
Lodola’s Lab – #LodolaLab_BtBs
last update: March 2024