Mercurio Sara, PhD

The activity is focused on the following research lines
Health research area BtBs UNIMIB
Health

Genetic Diseases, Neurodegenerative and neurological diseases, Stem cells and Regenerative Medicine

Keywords
Sox2, mouse, hippocampus, visual system, neurons, neural stem cells

Selected articles

Mercurio S.#, Alberti C., Serra L., Meneghini S., Berico P., Bertolini J., Becchetti A. and Nicolis S.K. # An early Sox2-dependent gene expression program required for hippocampal dentate gyrus development. Open Biol. 2021 Feb;11(2):200339. doi: 10.1098/rsob.200339. # corresponding author.

Mercurio S., Serra L., Motta A., Gesuita L., Sanchez Arrones L., Inverardi F., Foglio B., Barone C., Kaimakis P., Martynoga B., Ottolenghi S., Studer M., Guillemot F., Frassoni C., Bovolenta P., Nicolis S.K. Sox2 acts in thalamic neurons to control the development of retina-thalamus-cortex connectivity. iScience 15, 257–273, May 31, 2019. Contributed to journal cover. https://doi.org/10.1016/j.isci.2019.04.030

Bertolini J.A. *, Favaro R. *, Zhu Y. *, Pagin M., Ngan C.Y., Wong C.H., Tjong H., Vermunt M.W., Martynoga B., Barone C., Mariani J., Cardozo M.J., Tabanera N., Zambelli F., Mercurio S., Ottolenghi S., Robson P., Creyghton M.P., Bovolenta P., Pavesi G., Guillemot F., Nicolis S.K., Wei C.L. Mapping the Global Chromatin Connectivity Network for Sox2 Function in Neural Stem Cell Maintenance. Cell Stem Cell. 2019 Mar 7;24(3):462-476. (* joint first authors). DOI: https://doi.org/10.1016/j.stem.2019.02.004

Cerrato V. *, Mercurio S. *, Leto K. *, Fucà E., Hoxha E., Bottes S., Pagin M., Milanese M., Ngan C-Y, Concina G., Ottolenghi S., Wei C-L., Bonanno G., Pavesi G., Tempia F., Buffo A. and Nicolis S.K. Sox2 conditional mutation in mouse causes ataxic symptoms, cerebellar vermis hypoplasia, and postnatal defects of Bergmann glia. Glia 2018, Sep;66(9):1929-1946. (* joint first authors). https://doi.org/10.1002/glia.23448


Mercurio’s Lab – #MercurioLab_BtBs
last update: July 2021