Mercurio Sara, PhD
Assistant Professor of Genetics
room 1016, building U3-BIOS, tel.: +39 02 6448 3424
lab 3050 , building U3-BIOS
Keywords
Sox2, mouse, hippocampus, visual system, neurons, neural stem cells
Research projects
-Dissecting the role of Sox2 in neurons of the visual thalamus: insights into developmental visual disorders
Anno: 2022
Bando: Telethon multi-round Call for research projects 2021 – 2024
Enti finanziatori: FONDAZIONE TELETHON ETS
-PNRR per la Missione 4, componente 2 Investimento 1.1- Avviso 104/2022 | Dissection of the Sox2 gene regulatory network in the developing visual system
Anno: 2022
Bando: Bando PRIN 2022
Enti finanziatori: MINISTERO DELL'UNIVERSITA' E DELLA RICERCA (MUR)
Selected articles
Mercurio S.#, Alberti C., Serra L., Meneghini S., Berico P., Bertolini J., Becchetti A. and Nicolis S.K. # An early Sox2-dependent gene expression program required for hippocampal dentate gyrus development. Open Biol. 2021 Feb;11(2):200339. doi: 10.1098/rsob.200339. # corresponding author.
Mercurio S., Serra L., Motta A., Gesuita L., Sanchez Arrones L., Inverardi F., Foglio B., Barone C., Kaimakis P., Martynoga B., Ottolenghi S., Studer M., Guillemot F., Frassoni C., Bovolenta P., Nicolis S.K. Sox2 acts in thalamic neurons to control the development of retina-thalamus-cortex connectivity. iScience 15, 257–273, May 31, 2019. Contributed to journal cover. https://doi.org/10.1016/j.isci.2019.04.030
Bertolini J.A. *, Favaro R. *, Zhu Y. *, Pagin M., Ngan C.Y., Wong C.H., Tjong H., Vermunt M.W., Martynoga B., Barone C., Mariani J., Cardozo M.J., Tabanera N., Zambelli F., Mercurio S., Ottolenghi S., Robson P., Creyghton M.P., Bovolenta P., Pavesi G., Guillemot F., Nicolis S.K., Wei C.L. Mapping the Global Chromatin Connectivity Network for Sox2 Function in Neural Stem Cell Maintenance. Cell Stem Cell. 2019 Mar 7;24(3):462-476. (* joint first authors). DOI: https://doi.org/10.1016/j.stem.2019.02.004
Cerrato V. *, Mercurio S. *, Leto K. *, Fucà E., Hoxha E., Bottes S., Pagin M., Milanese M., Ngan C-Y, Concina G., Ottolenghi S., Wei C-L., Bonanno G., Pavesi G., Tempia F., Buffo A. and Nicolis S.K. Sox2 conditional mutation in mouse causes ataxic symptoms, cerebellar vermis hypoplasia, and postnatal defects of Bergmann glia. Glia 2018, Sep;66(9):1929-1946. (* joint first authors). https://doi.org/10.1002/glia.23448
Mercurio’s Lab – #MercurioLab_BtBs
last update: July 2021