Abstracts BtBsDay2020
Identification of spectroscopic markers of amyotrophic lateral sclerosis
Ami D.1, Ambrosio F.1, Natalello A.1
E-mail: diletta.ami@unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: Amyotrophic lateral sclerosis, FTIR microspectroscopy, multivariate analysis, protein aggregation, protein misfolding, tears
Effects of HSP proteins on FUS aggregates modulation
Arlati F.1, Zamprogno M.1, Levone BR.1, Barabino SML.1
E-mail: f.arlati7@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: FUS, protein aggregation, chaperones, HSP, DNA damage, ALS
Roasting process does not affect anti-inflammatory properties of coffee extracts
Artusa V.1, Ciaramelli C.1, Palmioli A.1, Airoldi C.1, Peri F.1
E-mail: v.artusa@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: coffee extract, phytochemicals, roasting, inflammation, cytokines
Dissecting the role of serine in neurological disorders
Badone B.1, Tripodi F.1, Coccetti P.1
E-mail: beatrice.badone@unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: Alzheimer’s Disease, hiPSC-astrocytes, neural stem cells, brain tissues, metabolism
Biofabrication of a vascularized 3D tissue in vitro model
Barbugian F.1,2, Bodet T. 2, Moroni L.2, Russo L.1, Nicotra F.1
E-mail: f.barbugian@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2Institute for Technology-Inspired regenerative Medicine (MERLN), Netherlands
Keywords: Regenerative medicine, Tissue Engineering, Biofabrication, Breast cancer, Vasculogenesis, Bioprinting, Additive Manufacturing, hydrogel
Enzymatic hydrolysis of Camelina sativa meal for carotenoids production by the yeast Rhodosporidium toruloides
Bertacchi S.1, Cantù C.1, Branduardi P.1
E-mail: s.bertacchi@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: Bio-based products, Renewable resources, Biorefinery, Camelina meal, Enzymatic hydrolysis, Rhodosporidium toruloides, Carotenoids
Charge patterning and phase separation propensity in IDPs: is there a possible interplay?
Bianchi G.1, Dell’Orto L.2, Longhi S.2, Brocca S.1
E-mail: g.bianchi31@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2CNRS and Aix-Marseille University, Laboratoire Architecture et Fonction des Macromolécules Biologiques (AFMB), UMR 7257, Marseille, France
Keywords: protein conformation, protein coacervation, distribution of electrostatic charges
Analysis of cadmium effect on neural cells energetic metabolism using Seahorse technology
Bovio F.1, Forcella M.1, Urani C.2, Fusi P.1
E-mail: f.bovio@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2Department of Earth and Environmental Sciences, University of Milan Bicocca, Milan, Italy
Keywords: cadmium, Seahorse, neural cells, energetic metabolism, glycolysis
Glucobrassicin production in yeast using a synthetic biology approach
Butti P.1, Maestroni L.1, Branduardi P.1
E-mail: p.butti@campus.unimib.it
1IndBiotech lab, Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: glucosinolates, yeasts, synthetic biology, golden gate assembly, CRISPR-Cas9, enzymes scaffolding
Study of extracellular matrix glycosignature in dictate cell fate using 3D glyco-conjugate biomaterials
Cadamuro F.1, Chiodo F.2, Nicotra F.1, Russo L.1
E-mail: f.cadamuro@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2Department of Molecular Cell Biology and Immunology, Amsterdam Infection & Immunity Institute and Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam 1081 HV, The Netherlands
Keywords: Glycans, Biomaterials, Extracellular matrix
Towards the valorisation of cinnamon bark extract residue: microbial fermentation for carotenoids production
Cantù C.1, Bertacchi S.1, Pagliari S.2, Bruni I.2, Labra M.2, Branduardi P.1
E-mail: c.cantu@campus.unimib.it
1IndBioTech Lab, Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2ZooPlantLab, Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: Cinnamon, Carotenoids, Rhodosporidium toruloides, Circular economy
Dual role of Dpb4 in the DNA damage response
Casari E.1, Gobbini E.1, Calabrese S.1, Clerici M.1, Longhese MP.1
E-mail: e.casari@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: DSB, checkpoint, resection, chromatin, S. cerevisiae
Abstract not available
Polymeric nanoparticles decorated for in vivo multimodal imaging
Cecchi S. 1, Rossi L.1, Nicotra F.1, Russo L.1
E-mail: s.cecchi@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: polymeric nanoparticles, click chemistry, multimodal imaging, in vivo detection, β-cells
NMR-based dissection of cocoa anti-amyloidogenic activity
Ciaramelli C.1,4, Palmioli A.1,4, De Luigi A.2, Colombo L.2, Sala G.3,4, Salmona M.2, Airoldi C.1,4
E-mail: carlotta.ciaramelli@unimib.it
1 BioOrgNMR Lab, Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2 Department of Molecular Biochemistry and Pharmacology, IRCCS- Istituto di Ricerche Farmacologiche “Mario Negri”, Milan, Italy
3 School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy
4 Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca, Milan, Italy
Keywords: Cocoa, flavanols, NMR, anti-amyloidogenic, Aβ peptides, Alzheimer’s disease
Developmental effects of β2V287L nAChR subunit on pyramidal neuron morphology in the neocortex
Colombo G.1, Modena D.2, Coatti A.1*, Amadeo A.2, Becchetti A.1
E-mail: g.colombo83@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2University of Milano, Milan, Italy
* Past affiliation
Keywords: epilepsy, sleep, nAChR, pyramidal neuron, cortex, dendrites, dendritic spines, ADSHE
A possible integrated model of hydroxycitric acid based on analyses in Saccharomyces cerevisiae
Croci G.1, Colombo S.1, Baroni MD.1,2, Martegani E.1
E-mail: g.croci4@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2Department of Biology, University of Padua, Padua, Italy
Keywords: Aging, Caloric restriction mimetics, Hydroxycitric acid, Autophagy
Synthesis and optimization of small molecules as modulators of Toll-like Receptor 4 (TLR4)
D’Amato S.1, Romerio A.1, Peri F.1
E-mail: s.damato@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: Innate immunity, TLR4 agonists, vaccine adjuvants, lipopolysaccharide
Abstract not available
Effects of short chain alcohol on Candida antarctica Lipase B
De Divitiis M.1, Mangiagalli M.1, Natalello A.1, Lotti M.1
E-mail: m.dedivitiis1@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: N435, CALB, organic solvents
Effects of Prebiotics and Probiotics on Human Gut Microbiota and Related Immune System: A Study on Healthy and Elderly Subjects
De Giani A.1, Sandionigi A.1, Zampolli J.1, Michelotti A.2, Tursi F.2, Labra M.1, Di Gennaro P.1
E-mail: alessandra.degiani@unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2CompLife Italia, Safety and Efficacy Lab, Italy
Keywords: Clinical study, Synbiotic, Prebiotics, Probiotics, Gut Microbiota
Cardoon roots valorization by combined microbial biotransformation for lactic acid production
Di Lorenzo RD.1, Branduardi P.1
E-mail: raffaella.dilorenzo@unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: Cardoon, Inulin, Lactic acid, Synthetic consortium
High-resolution imaging and high-content analysis of mitochondrial efficiency and OXPHOS relevance in grade II bladder cancer cells
Ducci G.1,2, Pasquale V.1,2, Campioni G.1,2, Ventrici A.1, Arrigoni E.1, Vanoni M.1,2, Vago R.3, Sacco E.1,2
E-mail: g.ducci@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2SYSBIO/ISBE.IT, Centre of Systems Biology, Milan, Italy
3Urological Research Institute, Division of Experimental Oncology, IRCCS San Raffaele Hospital, Milan, Italy
Keywords: bladder cancer, energy and redox metabolism, cellular bioenergetics, mitochondrial function, oxidative stress, operetta
Mechanism of action of new synthetic Toll-Like receptor 4 agonists for the development of innovative vaccine adjuvants
Gotri N.1, Facchini F.A.1, Romerio A.1, Luraghi A.1, Peri F.1
E-mail: n.gotri@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: TLR4, synthetic molecules, vaccine adjuvants, immunostimulators
Is “Post-Rest Potentiation” (PRP) a SERCA or NCX function index?
Leone J.1, Pane D.1, Ferè B.1, MS, Lodola F.1, Zaza A.1
E-mail: j.leone2@campus.unimib.it
1Laboratory of Cardiac Cellular Physiology, Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: Post-rest potentiation, SERCA, NCX, calcium transient, drug testing
The cellular response to DNA damage induced by R-loops
Longaretti M.1, Bonetti D.1
E-mail: m.longaretti4@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: R-loops, DNA Damage, replication stress, DDR
Abstract not available
Detection of PKA activity in Saccharomyces cerevisiae cell population using Fluorescence Resonance Energy Transfer (FRET) probes
Longoni E.1, Colombo S.1, Martegani E.1
E-mail: e.longoni15@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: Yeast, PKA, FRET, AKAR3, glucose
Glucosinolates as nutraceuticals: Process optimization and scale-up of Bio-based microbial production of glucobrassicin
Maestroni L.1, Butti P.1, Branduardi P.1
E-mail: l.maestronj@campus.unimib.it
1IndBiotech lab, Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: glucosinolates, circular economy, process design, yeasts, synthetic biology, golden gate assembly, CRISPR-Cas9, enzymes scaffolding
Engineered hybrid hydrogels as 3D bioprintable platform for preclinical investigations
Magli S.1, Crippa L.2, Ballarini E.2, Smith A.2, Cavaletti G.2, Magni F.2, Bertini S.3, Cosentino C.3, Nicotra F.1, Russo L.1
E-mail: s.magli1@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2School of Medicine and Surgery, University of Milano-Bicocca, Vedado al Lambro (MB), Italy
3Institute for Chemical and Biochemical Research G. Ronzoni, Milan, Italy
Keywords: Hybrid Hydrogel, Click Chemistry, Diels Alder, 3D model, Bioprinting
Overexpression of miR-133c and miR-362-3p in mouse oligodendroglioma could be part of a tumor suppression mechanism
Malighetti F.1, Barone C.1, Nicolis SK.1
E-mail: f.malighetti@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: miRNA, SOX2, oligodendroglioma, cancer stem cells, mouse, tumor suppressor gene
Effects of manganese ion on Antarctic esterase
Marchetti A.1, Mangiagalli M.1, Lotti M.1
E-mail: a.marchetti20@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: Extremozyme, psychrophiles, esterase, manganese, characterization, activity, structure
Synthesis of new potential inhibitors of biofilm formation for multivalent interaction
Marradi L.1, Rossi L.1, Russo L.1, Nicotra F.1, Titz A.2
E-mail: l.marradi@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2Helmholtz Institute for Pharmaceutical Research Saarland (HIPS); Saarbrucken, Germany
Keywords: P. Aeruginosa, biofilm, glycomimetic, conjugation, inhibitors, bacterium resistance, lectinB, multivalency
Development of a sustainable bioprocess for the production of Vitamin B9
Mastella L.1, Bertacchi S.1, Senatore VG.1, Labra M.1, Beltrani T.2, Branduardi P.1
E-mail: l.mastella@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2Laboratory for Resources Valorization (RISE), Department for Sustainability, ENEA- Italian National Agency for New Technologies, Energy and Sustainable Economic Development, Italy
Keywords: Saccharomyces cerevisiae, Scheffersomyces stipitis, folate, metabolic engineering, residual biomasses, industrial symbiosis
Protein metabolite interaction and metabolic flux sensing are involved in glucose control of Snf1/AMPK activity
Milanesi R.1, Tripodi F.1, Coccetti P.1
E-mail: r.milanesi2@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: Snf1/AMPK, Ras/PKA, glucose metabolism, protein metabolite interaction, signal transduction, flux sensing
3D in vitro advanced models based on bioprintable engineered hydrogels
Murenu N.1, Magli S.1, Russo L.1, Nicotra F.1
E-mail: n.murenu@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: ECM, Biopolymers, Hybrid Hydrogels, Diels Alder reaction, Bioprinting, 3D models, Bioinks
Cadmium elicits alterations in mitochondrial morphology and functionality in C3H10T1/2Cl8 mouse embryonic fibroblasts
Oldani M.1, Manzoni M.2, Villa A.M.1, Stefanini F.M.3, Melchioretto P.4, Monti E.2, Forcella M.1 ,Urani C.4,5, Fusi P.1,5
E-mail: m.oldani12@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2Department of Molecular and Translational Medicine (DMTM), University of Brescia, Brescia, Italy
3Department of Statistics, Computer Science, Applications, University of Florence, Florence, Italy
4Department of Earth and Environmental Sciences, University of Milano-Bicocca, Milan, Italy
5Integrated Models for Prevention and Protection in Environmental and Occupational Health, (MISTRAL), Interuniversity Research Center, Italy
Keywords: Cadmium Carcinogenesis, Cell metabolism, DNA damage Mitochondria, Reactive oxygen species
A Sox2-Fos-Socs3 gene regulatory network controls the self-renewal of Neural Stem Cells
Pagin M.1, Giubbolini S.1, Pernebrink M.2,5, Sambruni G.1,3, Barone C.1, Pitasi M.1, Mercurio S.1, Ottolenghi S.1, Pavesi G.3, Wei CL.4, Cantù C.2,5, Nicolis SK.1
E-mail: m.pagin1@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2WCMM and Department of Biomedical and Clinical Sciences, Linköping University, Sweden
3Department of Biosciences, University of Milano, Italy
4The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA
5Department of Biomedical and Clinical Sciences, Linköping University, Sweden
Keywords: Sox2, transcription factor, neural stem cells, self-renewal, long-range interactions, Socs3, Fos, rescue
Development of ultrasound assisted solid liquid extraction method for the recovery of bioactive compounds from cocoa shell by-product as natural source of functional ingredient
Pagliari S.1, Rastrelli L. 2, Campone L.1
E-mail: stefania.pagliari@unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2Department of Pharmacy, University of Salerno, Fisciano (SA), Italy
Keywords: Theobroma cacao, SALLE, chemometric analysis, Methylxanthines, UHPLC-HRMS-UV
Healthy compounds from vegetable matrices: an overview ranging from biodiversity to by-products
Davide P.1, Pagliari S.1, Giustra CM.1, Magoni C.1, Guzzetti L.1, Sacco G.1, Bruni I.1, Forcella M.1, Fusi P.1, Labra M.1
E-mail: davide.panzeri@unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: bioprospecting, sustainability, bioactivity, by-products, biodiversity
Three-dimensional models for the study of breast cancer metabolism
Pasquale V.1,2*, Campioni G.1,2*, Ducci G.1,2, Savore A.1,2, Sacco E.1,2, Vanoni M.1,3
E-mail: valentina.pasquale@unimib.it, g.campioni@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
1SYSBIO, Centre of Systems Biology, Milan, Italy
* VP and GC equally contributed to this manuscript
Keywords: three-dimensional models, spheroids, organoids, breast cancer, metabolism
The rediscovery of trehalose production by Saccharomyces cerevisiae
Pessina A.1, Vanoni M.1,2, Brambilla L.1,2
E-mail: a.pessina9@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2SYSBIO – Centre of Systems Biology, Milan, Italy
Keywords: Trehalose, S. cerevisiae, Glutamic acid, fed-batch, Metabolic engineering
Living in the metropolis: how landscape anthropization shapes morphology of two charismatic insect pollinators
Pioltelli E.1, Biella P.1, Tommasi N.1, Galimberti A.1 Labra M.1
E-mail: e.pioltelli@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: Pollination, Urbanization, Landscape, Ecology, Morphology
Sox2 and its targets in Neural Stem Cells self-renewal and differentiation
Pitasi M.1, Pagin M.1, Nicolis SK.1
E-mail: m.pitasi@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: Sox2, Socs3, Fos, NSCs, transcription factor, self-renewal, differentiation, transduction
Role of DNA damage response in R-Loops recognition and signalling
Pizzul P.1, Bonetti D.1
E-mail: p.pizzul@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: DNA damage, R-Loops, RNA-DNA Hybrids, Saccharomyces cerevisiae
Abstract not available
Evaluation of the prebiotic effects of new natural extracts on beneficial bacteria associated with human health
Racca T.1, De Giani A.1, Di Gennaro P.1
E-mail: tiziana.racca@unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: Prebiotics, Probiotics, Natural extracts, Health
Multimodal enhanced in vivo imaging of pancreatic β-cells using PGA-chitosan based nanoparticles
Rossi L.1, Russo L.1, Pignatelli C.1, Kerekes K.2, Körhegyi Z.2, Bodnar M.2, Kocsi J.2, Lindheimer F.3, Lindner M.3, Lindner S.3, Bartenstein P.3, Ziegler S.3, Nicotra F.1
E-mail: l.rossi58@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2BBS Nanotechnology, Debrecen, Hungary
3Department of Nuclear Medicine, Faculty of Medicine, University Hospital LMU, Munich, Germany
Keywords: in vivo targeting, multimodality, nanoparticles, pancreas, click chemistry
Integration of transcriptomics and metabolomics data to investigate metabolic heterogeneity in breast cancer cells
Schiesaro G.3, Damiani C.1,2,3, Pescini P.1,2, Di Filippo M.2,3
E-mail: g.schiesaro@campus.unimib.it
1Department of Informatics, Systems and Communication, University of Milan-Bicocca, Milan, Italy
2SYSBIO Centre of Systems Biology, Milan, Italy
3Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: Flux Balance Analysis, Systems Biology, Metabolism, Cancer, Genome Scale Model, Data Integration
Production of vitamin B9 from local residual biomasses
Senatore VG.1, Mastella L.1, Branduardi P.1
E-mail: v.senatore@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: Saccharomyces cerevisiae, Scheffersomyces stipitis, folate, metabolic engineering, residual biomasses, industrial symbiosis
β2-V287L nicotinic receptor subunit expression reduces glutamate release on fast-spiking neurons in layer V prefrontal cortex
Simonti M.1, Meneghini S.1, Becchetti A.1
E-mail: m.simonti@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: ADSHE, frontal lobe epilepsy, nicotinic receptor, glutamate release
Development of vault-based nanovectors in Pichia pastoris and antibody-mediated targeting investigation on cancer cell lines
Tomaino G.1, Pozzi M.1, Mazzucchelli M.1, Agresta A.1, Vanoni M.1,2, Frascotti G.1, Tortora P.1
E-mail: g.tomaino3@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2SYSBIO – Centre of Systems Biology, Italy
Keywords: Pichia pastoris, vault nanoparticle, cell targeting, breast cancer
DALIS in aging, inflammation and neurodegeneration
Torinesi RS.1, Gatti E.2, Grandori R.1, Vai M.1, Orlandi I.1
E-mail: r.torinesi@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2Centre d’Immunologie de Marseille-Luminy, CNRS-INSERM-Université de la Méditerranée, Campus de Luminy, Marseille, France
Keywords: DALIS, dendritic cell, protein aggregate, Saccharomyces cerevisiae
Solid phase synthesis of biopolymers for 3D intestinal ECM model
Valotti I.1, Cadamuro F.1, Nicotra F.1, Russo L.1
E-mail: i.valotti@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: Solid phase synthesis, Bio-inks, Biopolymers, 3D bioprinting, Collagen, Hyaluronic acid, Intestinal 3D model
Identification of novel gene asset of Rhodococcus opacus R7 for polyethylene degradation by RNA-seq approach
Zampolli J.1, Orro A.2, Milanesi L.2, Di Gennaro P.1
E-mail: jessica.zampolli@unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2Institute of Biomedical Technologies, National Research Council, CNR, ITB-CNR, Italy
Keywords: Rhodococcus genus, RNA-seq analysis, biodegradation, plastic, polyethylene
Effects of HSP proteins in DNA damage response
Zamprogno M.1, Arlati F.1, Levone BR.1, Barabino SML.1
E-mail: m.zamprogno@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
Keywords: FUS, HSP, DNA damage, ALS, ETO, RBP