Russo Laura, PhD

Assistant Professor
Laura Russo BtBs UNIMB

room 4020, buiding U3, tel. +39 02 6448 3462

lab 4045, buiding U4, tel. +39 02 6448 3393

lab 1024, buiding U28, tel. +39 02 6448 8245

laura.russo@unimib.it

see also: ResearchGate , Google Scholar , Linkedin , Twitter (@LRussoUnimib) , WebSite

The activity is focused on the following research lines
Health research area BtBs UNIMIB
HEALTH

Nanomedicine and Biomaterials, Stem cells and Regenerative Medicine

Keywords
BioOrganic chemistry, Glycoscience, Nanomedicne, 3D bioprinting, biomaterials

Background

Laura Russo is Assistant Professor at University of Milano-Bicocca, Adjunct Lecturer at National University of Ireland, Galway and Visiting Researcher at Cùram – Center for of Excellence of Biomaterials and Regenerative Medicine -  Ireland.

Since 2019 LR is also President of AlumniBicocca, the association of Alumni from University of Milano-Bicocca. Her research experience dates to 2010, as PhD student in the BioOrganic research group of University of Milano-Bicocca, working on a multidisciplinary project exploiting glycoscience in the field of nano- and bio-materials for tissue engineering. In 2010 LR joined the research group of Prof. Julian R. Jones, at Imperial College of London, as Visiting Researcher, working on hybrid biomaterials for osteochondral tissue regeneration. From 2013 to 2015 she worked, as Post Doc Fellow, at University of Milano-Bicocca, where she was unit coordinator of a research project funded by Cariplo Foundation on smart biomaterials for organoid cell cultures for cardiac tissue engineering.

In October 2016 Dr. Russo awarded a SFI Starting Investigator Research Grant (SIRG) at Cùram, National University of Ireland - Galway – where she started her research as Principal Investigator on Glycofunctionalized hydrogels and biomaterials for tissue engineering applications and cell biology studies.

In March 2017 she came back at the University of Milano – Bicocca where she got a position of Assistant Professor in Organic Chemistry, and maintained the position of visiting researcher at Cùram, and was also appointed Adjunct Lecturer at the National University of Ireland – Galway (Dept of Chemistry).

Awards and Recognition:

-September 2017 Junior Research Award for Organic Chemistry in Life Science of the Italian Chemical Society for her scientific contribute on organic chemistry applied to biomedical and life science field.
-October 2018 XVI International Award Federichino 2018. Federico II Foundation di Jesi, Palermo and Goppinghen.
-October 2016 Recognition of Minister of State for Training, Skills and Innovation, John Halligan TD - as “next leaders of research in Ireland, shaping the research community both in Ireland and internationally”

Research interest

Research interests of Dr. Russo are focused on 3D smart glyco-biomaterials and nanomaterials for cell studies and regenerative medicine, on 3D printable materials for biomedical applications. In particular she worked on nano- and biomaterials functionalization using a wide range of materials (organic, inorganic, polymeric, natural and synthetic), and smart functionalized hydrogel for 3D cell cultures. Dr Russo has also expertise in manipulating complex biomolecules such as carbohydrates. Her research activity to date has allow to the design and set up of different chemoselective ligation strategies for the covalent immobilization of several carbohydrates and peptides of biological interest on nanomaterials for tissue engineering applications.

Research areas

Health, Nanomedicine and Biomaterials, Tissue Engineering and 3D in vitro advanced model.

Active projects

-Ministero della Salute, RF‐2016‐02362946, Theoryenhancing Projects. Title: Dissecting the link between pulmonary stromal changes and lung cancer progression for biomarkers discovery and therapeutic intervention
-H2020-NMBP-15-2017- GA-760986, iNanoBIT ,Integration of Nano- and Biotechnology for beta-cell and islet Transplantation
-POR-FESR 2014-2020 Innovazione e Competitività. PROGETTI STRATEGICI DI RICERCA, SVILUPPO E INNOVAZIONE, Azione I.1.b.1.3-IMMUN-HUB – Sviluppo di nuove molecole di seconda generazione per immunoterapia oncologica.
-COST Action CA18132, Functional Glyconanomaterials for the Development of Diagnostics and Targeted Therapeutic Probes. (Country Representative, MC Member)

Finished projects

-Starting Investigator Research Grant (SIRG): Principal Investigator Award on the Project: Glyco-functionalised Hydrogel for Intervertebral Disc Tissue Repair. c/o National University of Ireland (NUI) Galway – Ireland
-CARIPLO FOUNDATION: project 2012-0891 (3/2013-2/2015): Smart nanostructured hydrogelsystems for generation of contractile cardiac organoids (PI Marco Rasponi, Politecnico di Milano

Selected articles

-Andras Dinnyes, Andrea Schnur, Suchitra Muenthaisong, Peter Bartenstein, Charles-Thibault Burcez, Neal Burton, Clemens Cyran, Pierre Gianello, Elisabeth Kemter, Gabor Nemeth, Francesco Nicotra, Eszter Prepost, Yi Qiu, Laura Russo, Andras Wirth, Eckhard Wolf, Sibylle Ziegler, Julianna Kobolak. Integration of Nano- and Biotechnology for Beta-cell and Islet Transplantation in Type-1 Diabetes Treatment. Cell Proliferation, accepted (IF 5.039) DOI: 10.1111/cpr.12785

-Carlos V. Montefusco-Pereira, Beatrice Formicola, Adriely Goes, Francesca Re, Claudia A. Marrano, Francesco Mantegazza, Cristiane Carvalho-Wodarz, Gregor Fuhrmann, Enrico Caneva, Francesco Nicotra, Claus-Michael Lehr, Laura Russo*. Coupling quaternary ammonium surfactants to the surface of liposomes improves both antibacterial efficacy and host cell biocompatibility. European Journal of Pharmaceutics and Biopharmaceutics, 2020 149, 12-20

-G. Marsico, L. Russo, F. Quondamatteo, A. Pandit. Glycosylation and Integrin Regulation in Cancer. Trends in Cancer. 2018, 4, 537-552.

-J. Nicolas, S. Magli, L. Rabbachin, S. Sampaolesi, F. Nicotra, L. Russo. 3D Extracellular Matrix Mimics: Fundamental Concepts and Role of Materials Chemistry to Influence Stem Cell Fate. Biomacromolecules, 2020. https://pubs.acs.org/doi/abs/10.1021/acs.biomac.0c00045

 

International and national collaboration

-NABBA project: 8 international collaborations, see http://nabbaproject.eu/
-iNanoBIT project: 7 international collaborations, see http://inanobit.eu/
-IMMUN-HUB project: 5 national external collaboration (italfarmaco S.p.a., Istituti Clinici Scientifici Maugeri, CheckMab S.r.l., Aphad S.r.l., -Istituto Nazionale Tumori di Napoli Pascale) and 7 UNIMIB groups
-Ministero della Salute, RF‐2016‐02362946: Istituto Nazionale dei Tumori di Milano, Dr. Luca Roz, Dr. Giulia Bertolini.
-Progetto 3D-printing e biomateriali per 3D testing: Istituto Biochimico Ronzoni (Dr. Sabrina Bertini), Ospedale San Raffaele (Dr. Antonio Citro), Humanitas (Prof. Roberto Rusconi)

 


Russo’s Lab – #RussoLab_BtBs
last update April 2020