Palmioli Alessandro, PhD
Assistant Professor of Organic Chemistry
room 3053, building U3, tel.: +39 02 6448 3309
lab 4054, building U3, tel. +39 02 6448 3422
see also: Linkedin, ResearchGate, ORCID ID, Google Scholar, Scopus
Keywords
Bioorganic chemistry, Bioactive molecules, Natural compounds, Drug discovery, NMR spectroscopy, MS spectrometry, Metabolomics
Research interest
My research interests are mainly focused on the design and synthesis of bioactive compounds and molecular tools for biomedical and biotechnological applications. More recently, I have moved on the characterization of complex mixtures of natural origin aimed at the identification and isolation of chemoprotective compounds.
Research projects
MicroBiomA-S - Exploring the diversity of soil microbes and their biomolecules in Victoria Land, funded by PNRA 2018
BacHounds - Supramolecular nanostructures for bacteria detection, funded by PRIN2017
Selected articles
-Palmioli, A.; Sperandeo, P.; Bertuzzi, S.; Polissi, A.; Airoldi, C., On-cell saturation transfer difference NMR for the identification of FimH ligands and inhibitors. Bioorganic Chemistry 2021, 112, 104876. http://dx.doi.org/10.1016/j.bioorg.2021.104876
-Palmioli, A.; Nicolini, G.; Tripodi, F.; Orsato, A.; Ceresa, C.; Donzelli, E.; Arici, M.; Coccetti, P.; Rocchetti, M.; La Ferla, B.; Airoldi, C., Targeting GRP receptor: design, synthesis and preliminary biological characterization of new non-peptide antagonists of bombesin. Bioorganic Chemistry 2021, 109, 104739. http://dx.doi.org/10.1016/j.bioorg.2021.104739
-Palmioli, A.; Bertuzzi, S.; De Luigi, A.; Colombo, L.; La Ferla, B.; Salmona, M.; De Noni, I.; Airoldi, C., bioNMR-based identification of natural anti-Aβ compounds in Peucedanum ostruthium. Bioorganic Chemistry 2019, 83, 76-86. http://dx.doi.org/10.1016/j.bioorg.2018.10.016
-Palmioli, A.; Ciaramelli, C.; Tisi, R.; Spinelli, M.; De Sanctis, G.; Sacco, E.; Airoldi, C., Natural Compounds in Cancer Prevention: Effects of Coffee Extracts and Their Main Polyphenolic Component, 5-O-Caffeoylquinic Acid, on Oncogenic Ras Proteins. Chemistry – An Asian Journal 2017, 12 (18), 2457-2466. http://dx.doi.org/10.1002/asia.201700844
Palmioli’s Lab – #PalmioliLab_BtBs
last update: April 2022