Tisi Renata Anita, PhD

Associate Professor in Molecular Biology

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Renata Tisi BtBs UNIMIB

 

room 5017, building U4, tel. +39 02 6448 3522

lab 5044, building U4, tel. +39 02 6448 3534

renata.tisi@unimib.it

The activity is focused on the following research lines

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Health research area BtBs UNIMIB
Health

Cancer, Drug Discovery and Pharmacology, Genetic Diseases, Neurodegenerative and neurological diseases, Systems biology

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industrial biotechnology research area BtBs UNIMIB
Industrial Biotechnology

Molecular modeling and Structural Biology

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Research group

Vertemara Jacopo – PostDoc
room 4064, building U3,  tel. +39 02 6448 3473, jacopo.vertemara@unimib.it

Keywords

Homology modelling; Small molecule-protein docking; Protein-protein docking

Research areas

-Signal transduction
-Computational Biology
-Systems Biology
-Biological systems analysis, modelling and simulation

Selected publications

-Bonetti D, Rinaldi C, Vertemara J, et al. (2020) DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends. Nucleic Acids Res. 2020;48(5):2424–2441. doi:10.1093/nar/gkz1203

-Gobbini E, Cassani C, Vertemara J, et al. (2018) The MRX complex regulates Exo1 resection activity by altering DNA end structure. EMBO J. 2018;37(16):e98588. doi:10.15252/embj.201798588

-Niedzwiecka K, Tisi R, Penna S, Lichocka M, Plochocka D, Kucharczyk R. Two mutations in mitochondrial ATP6 gene of ATP synthase, related to human cancer, affect ROS, calcium homeostasis and mitochondrial permeability transition in yeast. Biochim Biophys Acta Mol Cell Res. 2018;1865(1):117–131. doi:10.1016/j.bbamcr.2017.10.003

-Palmioli A, Ciaramelli C, Tisi R, et al. Natural Compounds in Cancer Prevention: Effects of Coffee Extracts and Their Main Polyphenolic Component, 5-O-Caffeoylquinic Acid, on Oncogenic Ras Proteins. Chem Asian J. 2017;12(18):2457–2466. doi:10.1002/asia.201700844


Tisi’s Lab – #TisiLab_BtBs
last update May 2021