| Dipartimento di Biotecnologie e Bioscienze BtBs

BtBsDay2026 Poster session (P11-P20)

Giornata del Dipartimento di Biotecnologie e Bioscienze 2026

Programma BtBsDay 2026

Poster session - Galleria della Scienza (U3-U4)

P11_From bycatch to barcodes: Integrating trawling surveys and eDNA in the Gulf of Castellammare (Sicily)

Poster presenter - Giannetto Sabrina

Giannetto S.1, Verduci V.1,2, Mangano C.2,3, Berlino M. 2,3 Labra M.1,2, Frigerio J.1,2, Galimberti A.1,2, Sará G.2,4, Maggioni D.1,2
E-mail: s.giannetto1@campus.unimib.it
1 Department of Biotechnologies and Biosciences, University of Milano-Bicocca, Italy
2 National Biodiversity Future Center (NBFC), Palermo, Italy
3 Stazione Zoologica Anton Dohrn, Sicily Marine Centre, Palermo, Italy
4 Earth and Marine Sciences Department, University of Palermo, Palermo, Italy

Keywords: marine biodiversity, DNA barcoding, fishing, Mediterranean sea, Nanopore sequencing

#BtBsDay - #BtBsDayP11

P11_ABSTRACT POSTER_Giannetto Sabrina

P12_Modeling Glioblastoma heterogeneity using 3D cerebral organoids

Poster presenter - Berni Valentina

Valentina Berni1,2, Martina Giambra1,2, Chiara Riccardi3, Sara Ferro3, Angela Bentivegna1, Rossella Galli4, Rosa Maria Moresco1, Veronica Krenn3,5
E-mail: v.berni1@campus.unimib.it
1 School of Medicine and Surgery, University of Milano-Bicocca, 20900 Monza, Italy
2 PhD program in Neuroscience, University of Milano-Bicocca, 20900 Monza, Italy
3 Department of Biotechnology and Bioscience, University of Milano-Bicocca, Milano, Italy
4 Neural Stem Cell Biology Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan,Italy
5 Human Technopole Early Career Fellow

Keywords: GBM, organoids, patient-derived, GLICO model

#BtBsDay - #BtBsDayP12

P12_ABSTRACT POSTER_Berni Valentina

P13_Expanding Kluyveromyces marxianus synthetic biology toolbox for streamlining natural dyes cell factories construction

Poster presenter - Pacaccio Antonia

Antonia Pacaccio1,2, Pietro Butti1,2, Valeria Mapelli1, Paola Branduardi1, John P. Morrissey2
E-mail: a.pacaccio@campus.unimib.it
1IndBioTech Lab, Department of Biotechnology and Biosciences, University of Milano Bicocca, Milan, Italy
2School of Microbiology, University College Cork, Cork, Ireland

Keywords: Kluyveromyces marxianus, chassis strains, metabolic engineering, natural dyes, tryptophan

#BtBsDay - #BtBsDayP13

P13_ABSTRACT POSTER_Pacaccio Antonia

P14_Metabolic engineering and in silico modelling for evaluating ethylene glycol assimilation as a carbon source in Saccharomyces cerevisiae

Poster presenter - Pilerci Gaia

Gaia Pilerci1, Fiorella Masotti1, Riccardo Milanesi1, Vittorio Giorgio Senatore1, Immacolata Serra1, Dario Pescini2, Paola Branduardi1
E-mail: g.pilerci@campus.unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, Italy
2 Department of Statistics and Quantitative Methods, University of Milano-Bicocca, Milan, Italy

Keywords: S. cerevisiae, metabolic coupling, ethylene glycol, selection strain, in silico modelling

#BtBsDay - #BtBsDayP14

P14_ABSTRACT POSTER_Pilerci Gaia

P15_Characterization of a novel Pictet–Spenglerase toward the biosynthesis of new plant natural product scaffolds

Poster presenter - Bellusci Francesco

Bellusci Francesco1, Arboritanza Daniele1, Berlanda Davide2, Serra Immacolata1, Branduardi Paola1
E-mail: f.bellusci1@campus.unimib.it
1 Department of Biotechnology and Biosciences, University of Milan-Bicocca, 20126 Milan, Italy
2 R&D department, Indena S.p.A., 20049 Settala (MI) - Italy

Keywords: Pictet–Spenglerase - Plant natural products – Biocatalysis - Benzylisoquinoline alkaloids (BIAs)

#BtBsDay - #BtBsDayP15

P15_ABSTRACT POSTER_Bellusci Francesco

P16_Guarding European biodiversity: Molecular early-warning tools for invasive alien plants of Union concern

Poster presenter - Verduci Valentina

Valentina Verduci1,2,3, Frigerio J.1,2, Cavenago D.1, Lozano V.2,4, Brundu G.2,4, Spano D.2,4, Labra M.1,2
E-mail: v.verduci1@campus.unimib.it
1 Department of Biotechnologies and Biosciences, University of Milano-Bicocca, Italy
2 National Biodiversity Future Center (NBFC), Palermo, Italy
3 Earth and Marine Sciences Department, University of Palermo, Palermo, Italy
4 Department of Agricultural Sciences, University of Sassari, Sassari, Italy

Keywords: invasive species, eLAMP, early detection, eDNA

#BtBsDay - #BtBsDayP16

P16_ABSTRACT POSTER_Verduci Valentina

P17_Valorisation of phenolic compounds from lignocellulosic wastes using a new engineered E. coli strain

Poster presenter - Vaccaroni Francesco

Francesco Vaccaroni1, Alex Pessina1,2, Mouna Attafi1, Chiara Damiani1,2, Luca Brambilla1,2, Gianluca Molla3, Elena Rosini3, Loredano Pollegioni3, Marco Vanoni1,2
Corresponding author: f.vaccaroni@campus.unimib.it; alex.pessina@unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca
2 SYSBIO – Centre of Systems Biology, Italy
3 “The Protein Factory 2.0” Lab, Department of Biotechnology and Life Sciences, University of Insubria

Keywords: E. coli, lignocellulosic wastes, ferulic acid, vanillin, CRISPR/Cas9, bioreactor

#BtBsDay - #BtBsDayP17

P17_ABSTRACT POSTER_Vaccaroni Francesco

P18_Beyond viability: comparative functional evaluation of live and inactivated industrial biomasses of probiotic lactobacilli

Poster presenter - Pierallini Elena

Elena Pierallini1, Giacomo Mantegazza1,2, Beatrice Pizzelli1, Fabio Angelini1, Simone Guglielmetti1
E-mail: e.pierallini@campus.unimib.it
1 μbEat Lab, Department of Biotechnology and Biosciences (BtBs), University of Milano-Bicocca, Piazzadella Scienza 4, 20126 Milan, Italy
2 Division of Food Microbiology and Bioprocesses, Department of Food, Environment, and NutritionalScience, Università degli Studi Di Milano, Via Celoria 2, 20133 Milan, Italy

Keywords: Probiotics, Paraprobiotics, Postbiotics, Lactobacilli, Caco-2 cells, NF-κB, TLR2.

#BtBsDay - #BtBsDayP18

P18_ABSTRACT POSTER_Pierallini Elena

P19_Molecular Dynamics Investigation of O₂ Diffusion Mechanisms in the Protective CbA5H Hydrogenase

Poster presenter - Fossati Mattia Pietro

Mattia P. Fossati1, Jacopo Vertemara1, Federica Arrigoni1, Giuseppe Zampella1, Luca Bertini1, Luca De Gioia1
E-mail: m.fossati28@campus.unimib.it
1 Department of Biotechnology and Biosciences, Univ. degli Studi Milano-Bicocca, Milano, IT

Keywords: Biocatalysis, [FeFe]-Hydrogenase, Molecular Dynamics, O2-protection, H2-production.

#BtBsDay - #BtBsDayP19

P19_ABSTRACT POSTER_Fossati Mattia Pietro

P20_Genome-Scale Transcriptional and Metabolic Profiling of Rhodococcus opacus R7 During Polyethylene Degradation

Poster presenter - Vincenti Valentina

Vincenti V.1, Salvadori M. 1, Mangiagalli M.1, Lotti M.1, Ami D1, Natalello A.1, Bertini L.1, Arrigoni F.1, Di Gennaro P.1, Zampolli J.1
E-mail: v.vincenti1@campus.unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, Italy

Keywords: Rhodococcus genus, polyethylene, plastic-degrading enzymes, multicopper oxidases, laccases, oxygenases, lipases

#BtBsDay - #BtBsDayP20

P20_ABSTRACT POSTER_Vincenti Valentina

BtBsDay2026 Poster session (P01-P10)

Giornata del Dipartimento di Biotecnologie e Bioscienze 2026

Programma BtBsDay 2026

Poster session - Galleria della Scienza (U3-U4)

P01_Rhodotorula toruloides for carotenoid production using waste hardwood biomass

Poster presenter - Bertacchi Stefano

Stefano Bertacchi,a,b Francesca Sabatini,b,c Giovanni Maria Bernardinia, Matilde Dameria, Veronica Termopoli,b,c Danilo Porroa,b, Marco Orlandi,b,c Heiko Lange, b,c,d,* Paola Branduardi a,b,*
E-mail: stefano.bertacchi@unimib.it
a Department of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy
b NBFC – National Biodiversity Future Center, 90133 Palermo, Italy
c Department of Earth and Environmental Sciences, University of Milano-Bicocca, 20126 Milan, Italy
d Biochemical Process Engineering, Division of Chemical Engineering, Department of Civil, Environmental and Natural Resources Engineering, Luleå University of Technology, SE-971 87 Luleå, Sweden

Keywords: Rhodotorula toruloides, Carotenoids, Biodiversity valorisation, Biorefinery, Lignocellulosic biomass, Enzymatic hydrolysis

#BtBsDay - #BtBsDayP01

P01_ABSTRACT POSTER_Bertacchi Stefano

P02_A long-range enhancer at -52 kb drives expression of the COUP-TFII transcription factor in erythroid cells

Poster presenter - Fabiano Martina

Martina Fabiano1, Valentina Pastori1, Agata Labedz1,7,8, Maria Simanovich2, Carlotta Frigo1, Thijs Verheul2, Ludovica Proietti3,9, Florian Grebien3,4,5, Elisabetta Citterio1,6, Sjaak Philipsen2# and Antonella Ellena Ronchi1#
E-mail: martina.fabiano@unimib.it
1Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano-Bicocca, Milan, Italy
2Erasmus MC Department of Developmental Biology, P.O. Box 2040, 3000CA Rotterdam, The Netherlands
3Centre of Biological Sciences, University of Veterinary Medicine Vienna, Austria
4St. Anna Children’s Cancer Research Institute (CCRI), Vienna, Austria
5CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
6Department of Life Science, Health, and Health Professions, Link Campus University, Rome, Italy
7Present address: International Centre for Translational Eye Research, Warsaw, Poland
8Present address: Institute of Physical Chemistry, Polish Academy of Sciences, Warsaw, Poland
9Present address: Computational Biology Research Centre, Human Technopole Milan, Italy
# Co-Corresponding Authors

Keywords: Erythropoiesis, orphan nuclear receptor, COUP-TFII, hemoglobin switching

#BtBsDay - #BtBsDayP02

P02_ABSTRACT POSTER_Fabiano Martina

P03_COUP-TFII regulates hemoglobin switching by activating the BCL11A-XL repressor LIN28B and directly binding δ and β globin promoters in fetal versus adult erythroid cells

Poster presenter - Frigo Carlotta

Carlotta Frigo 1*, Valentina Pastori 1*, Gianluca Zambanini 2, 3, 4*, Martina Fabiano 1, Sajeela Ahmed 1, Elisabetta Citterio 1,5, Claudio Cantù 2,3,6 ^ and Antonella E. Ronchi 1^
E-mail: c.frigo1@campus.unimib.it
1 Dipartimento di Biotecnologie e Bioscienze, Università degli Studi di Milano-Bicocca, Milan, Italy.
2 Wallenberg Centre for Molecular Medicine, Linköping University, Linköping, Sweden.
3 Division of Molecular Medicine and Virology, Department of Biomedical and Clinical Sciences, Faculty of Medicine and Health Sciences, Linköping University, Linköping, Sweden.
4 Present address: Max-Planck-Institut für molekulare Genetik, Berlin, Germany.
5 Department of Life Science, Health, and Health Professions, LINK Campus University, Rome, Italy.
6 Science for Life Laboratory – SciLifeLab, Linköping University, 58185 Linköping, Sweden
*Co-First Authors
^ Co-Corresponding Authors

Keywords: Erythropoiesis, Transcriptional regulation, Hemoglobin switching, CUT&RUN

#BtBsDay - #BtBsDayP03

P03_ABSTRACT POSTER_Frigo Carlotta

P04_Cadmium affects mitochondrial functionality and induces mitochondrial fission in differentiated neural cells

Poster presenter - Simeoni Alice

Alice Simeoni1, Federica Bovio1, Chiara Urani2, Matilde Forcella1, Paola Fusi1
E-mail: a.simeoni1@campus.unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, 20126, Milano, Italy
2 Department of Earth and Environmental Sciences, University of Milano-Bicocca, 20126, Milano, Italy

Keywords: Cadmium; Neurotoxicity; SH-SY5Y cell line; Metabolism; Mitochondria; Seahorse.

#BtBsDay - #BtBsDayP04

P04_ABSTRACT POSTER_Simeoni Alice

P05_Acteoside exerts neuroprotective effects by preventing α-synuclein aggregation and oxidative stress

Poster presenter - Spandri Giorgia

Giorgia Spandri1, Alessia Lambiase1,2, Hind Moukham2, Elisa Toini1,2, Giovanni Zecca1,2, Carlo Santambrogio1, Maura Brioschi1, Fabrizio Grassi1,2, Farida Tripodi1,2, Paola Coccetti1,2, Massimo Labra1,2
E-mail: g.spandri@campus.unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, Italy.
2 National Biodiversity Future Center (NBFC), Palermo, Italy.

Keywords: Verbascum thapsus, verbascoside, Parkinson’s disease, protein aggregation

#BtBsDay - #BtBsDayP05

P05_ABSTRACT POSTER_Spandri Giorgia

P06_Role of Tel1 in promoting DNA end-tethering

Poster presenter - Pagnotta Federica

Carlo Rinaldi1, Federica Pagnotta1, Maria Pia Longhese1
E-mail: f.pagnotta3@campus.unimib.it
1 University of Milano-Bicocca

Keywords: Tel1, Rad9, DSBs, end-tethering, DNA damage response, S. cerevisiae

#BtBsDay - #BtBsDayP06

P06_ABSTRACT POSTER_Pagnotta Federica

P07_Advancing Human Brain Modeling with a Novel Microglia-Containing Organoid System: Validation and Strategies to Overcome Current Limitations

Poster presenter - Ferro Sara

Sara Ferro1, Anna Cascio1,2, Paolo Vaccari1 , Stefania Giussani3, Oliver Harschnitz3, Veronica Krenn1,4,5
E-mail: sara.ferro@unimib.it
1 Department of Biotechnology and Bioscience, University of Milan-Bicocca, Milan, Italy
2 DIMET PhD School, Dept. of Medicine and Surgery, University of Milan – Bicocca, Milan, Italy
3 Neurogenomics Research Centre, Human Technopole, Milan, Italy
4 Early Career Fellow, Human Technopole, Milan, Italy
5 Milan Center for Neuroscience (NeuroMI), Italy

Keywords: microglia, human brain organoids (hBOs), human embryonic ste

#BtBsDay - #BtBsDayP07

P07_ABSTRACT POSTER_Ferro Sara

P08_Dechipering the diverse role of Gal4 transcription factor in the regulation of central carbon metabolism of Saccharomycetaceae yeasts

Poster presenter - De Lisi Angela Maria

Angela Maria De Lisi1, Riccardo Milanesi1, Valeria Mapelli1, Paola Brandaurdi1
E-mail: a.delisi@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, Italy

Keywords: Saccharomycetaceae, Metabolism regulation, Transcription factor, Biodiversity, Evolution, Gal4

#BtBsDay - #BtBsDayP08

P08_ABSTRACT POSTER_De Lisi Angela Maria

P09_Sae2 integrates CDK and checkpoint phosphorylation to coordinate MRX cleavage with checkpoint attenuation

Poster presenter - Gnugnoli Marco

Marco Gnugnoli1,2, Erika Casari1,2, Paolo Pizzul1, Renata Tisi1 and Maria Pia Longhese1
E-mail: marco.gnugnoli@unimib.it
1 University of Milano Bicocca, Italy
2 These authors contributed equally

Keywords: DNA damage; Sae2; checkpoint; CDK, double-strand breaks; MRX

#BtBsDay - #BtBsDayP09

P09_ABSTRACT POSTER_Gnugnoli Marco

P10_Stn1 supports Mec1 function in protecting stalled replication forks from degradation

Poster presenter - Milani Luca Edoardo

Luca Edoardo Milani1, Erika Casari1, Flavio Corallo1, Renata Tisi1, Maria Pia Longhese1
E-mail: l.milani20@campus.unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, Italy

Keywords: yeast, replication stress, genome stability, checkpoint, Mec1, CST

#BtBsDay - #BtBsDayP10

P10_ABSTRACT POSTER_Milani Luca Edoardo

BtBsDay2026 Short talks (ST01-ST12)

Giornata del Dipartimento di Biotecnologie e Bioscienze 2026

Programma BtBsDay 2026

Short Talks - Sironi room (U4-08)

ST01_Inhibition of the Hexosamine Biosynthetic Pathway Impairs PIKK Maturation and Induces a BRCAness-Like Phenotype in Triple-Negative Breast Cancer

Speaker - Taverna Gabriele

Gabriele Taverna1, Barbara Zerbato1, Giulia Monterosso1, Eleonora Foti1, Ester Gallo1, Cinzia Bragato2, Lorenzo Taglietti2, Barbara La Ferla2, Domenica Scumaci3, Ferdinando Chiaradonna1.
E-mail: gabriele.taverna@unimib.it
1Milano-Bicocca University, department of Biotechnology and Bioscience – BTBS, Italy.
2Milano-Bicocca University, department of Earth and Environmental Science – DISAT, Italy
3Magna Graecia University of Catanzaro, department of Experimental and Clinic Medicine – DMSC, Italy

Keywords: Breast cancer, HBP, FR054, ATM, ATR, DNA-PK, BRCA1, Zebrafish.

#BtBsDay - #BtBsDayST01

ST01_ABSTRACT SHORT TALK_Taverna Gabriele

ST02_Different Lenses, Same Target: NMR Spectroscopy and Other Biophysical Tools for the Comprehensive Characterization of Prenylflavonoids Anti-Amyloidogenicity

Speaker - Molteni Linda

Linda Molteni1, Chiara Bruzzone1, Diletta Ami1,2, Ada De Luigi3, Laura Colombo3, Luca Moretti1, Antonino Natalello1,2, Alessandro Palmioli1,2, Cristina Airoldi1,2
E-mail: l.molteni@campus.unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, P.zza della Scienza 2, 20126 Milan, Italy.
2 NeuroMI, Milan Center for Neuroscience, University of Milano-Bicocca, 20126 Milano, Italy.
3 Department of Molecular Biochemistry and Pharmacology - Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via M. Negri 2, 20156 Milano, Italy.

Keywords: Xanthohumol, Aβ1-42, NMR, FTIR, AFM

#BtBsDay - #BtBsDayST02

ST02_ABSTRACT SHORT TALK_Molteni Linda

ST03_Harnessing Mirror-Image Peptides: Nanoparticle Vectors for Nucleic Acid Delivery in Cancer Treatment

Speaker - Banfi Andrea

Andrea Banfi1, Lucia Salvioni1, Miriam Colombo1, Davide Prosperi1
E-mail: a.banfi17@campus.unimib.it
1 NanoBioLab, Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

Keywords: peptide-based nanoparticles, targeted therapy, nucleic acids nanodelivery, immunotherapy, cancer

#BtBsDay - #BtBsDayST03

ST03_ABSTRACT SHORT TALK_Banfi Andrea

ST04_A natural modulator of the PKA and AMPK signaling regulates lipid metabolism in a steatosis model

Speaker - Moukham Hind

Hind Moukham¹, Andrea Sanguedolce¹, Giorgia Spandri¹, Alessia Lambiase¹², Valentina Santoro²³, Anna Lisa Piccinelli²³, Farida Tripodi¹², Paola Coccetti¹²
E-mail: h.moukham@campus.unimib.it
¹Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, Italy
²National Biodiversity Future Center (NBFC), Palermo, Italy
³Department of Pharmacy, University of Salerno, Fisciano, Italy

Keywords: NAFLD, Flavonoids, Lipolysis, Lipohagy, Lipid droplets, HepG2 cells, signaling

#BtBsDay - #BtBsDayST04

ST04_ABSTRACT SHORT TALK_Moukham Hind

ST05_Cellular consequences of non-ablative radiotherapy, a novel approach to ventricular tachycardias

Speaker - Maniezzi Claudia

Claudia Maniezzi1, Stefano Busti1, Angela S. Maione2, Elena Sommariva2, Francesco P. Cammarata3, Giusi I. Forte3, Gaetano M. De Ferrari4, Francesco Lodola1, Antonio Zaza1
E-mail: claudia.maniezzi@unimib.it
1 University of Milano-Bicocca, Milan, Italy
2 Unit of Inherited Cardiomyopathies, Centro Cardiologico Monzino IRCCS, Milan, Italy
3 Institute of Bioimaging and Complex Biological Systems, National Research Council, Cefalù, Italy &National Institute for Nuclear Physics, Laboratori Nazionali del Sud, Catania, Italy
4 Unit of Cardiology, Department of Medical Sciences, University of Turin, Turin Italy & Division ofCardiology, Molinette Hospital, Città della Salute e della Scienza, Turin, Italy

Keywords: non-ablative radiotherapy, Na+ current, ROS, CaMKII

#BtBsDay - #BtBsDayST05

ST05_ABSTRACT SHORT TALK_Maniezzi Claudia

ST06_From Cells to Circuits: Ethical Challenges and Opportunities in 3Rs-Aligned Modeling of Sleep Disorders

Speaker - Grandi Laura Clara

Laura Clara Grandi1,2, Francesca Gullo1, Andrea Becchetti1
E-mail: laura.grandi@unimib.it
1 Dipartimento di Biotecnologie e Bioscienze, Università di Milano Bicocca, Milano, Italia
2 Dipartimento di medicina sperimentale e clinica, Università degli studi di Firenze, Firenze, Italia

Keywords: Narcolepsy, Epilepsy, Sleep disorders, 3Rs, Animal models, Neuronal cultures, Brain slices, Translational neuroscience

#BtBsDay - #BtBsDayST06

ST06_ABSTRACT SHORT TALK_Grandi Laura Clara

ST07_HCN4 misregulation affects the early differentiation process of mouse embryonic stem cells

Speaker - Arici Martina

Martina Arici1, V. Pastori1, P. Benzoni2, R. Pensotti1, A. Metallo1, A. Ronchi1, M. Rocchetti1
E-mail: martina.arici@unimib.it
1 University of Milano-Bicocca, Italy
2 University of Milano, Italy

Keywords: HCN4, differentiation, pacemaker channel, mESC, cardiac development

#BtBsDay - #BtBsDayST07

ST07_ABSTRACT SHORT TALK_Arici Martina_RESERVED_Confidential Information

ST08_Electrochemical and computational methods as a combined approach to study redox enzymes

Speaker - Fasano Andrea

Andrea Fasano1, Federica Arrigoni1, Lara Callea1, Vincent Fourmond2, Luca Bertini1, Christophe Léger2, Luca de Gioia1
E-mail: andrea.fasano@unimib.it
1 Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, 20126, Italy
2 Laboratoire de Bioénergétique et Ingénierie des Protéines CNRS, Aix Marseille Université, Marseille13402, France

Keywords: Redox enzymes; O2 inhibition; Quantum mechanics; Protein film electrochemistry

#BtBsDay - #BtBsDayST08

ST08_ABSTRACT SHORT TALK_Fasano Andrea

ST09_The university campus microbiome: ecological drivers of skin–gut–environment microbial interactions

Speaker - Ghisleni Giulia

Giulia Ghisleni1, Alice Armanni1, Sara Fumagalli1, Jessica Zampolli1, Patrizia Di Gennaro1*, Antonia Bruno1*
E-mail: giulia.ghisleni@unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca

Keywords: Microbiome; Human–environment interactions; Skin microbiome; Gut microbiome; Built environment; Urbanization; University microbiome; 16S rRNA gene sequencing

#BtBsDay - #BtBsDayST09

ST09_ABSTRACT SHORT TALK_Ghisleni Giulia

ST10_Spatial Flux Balance analysis reveals Warburg heterogeneity in renal tumors and lactate-consuming niches in colorectal cancer

Speaker - Lapi Francesco

Davide Maspero1,x , Giovanni Marteletto2,x, Francesco Lapi3,x, Bruno G. Galuzzi4,5,6, Irene Ruano1 , Ben Vandenbosch7, Ke Yin7, Sabine Tejpar7, Alex Graudenzi9, Holger Heyn1,8 , Anna Pascual-Reguant1,+ , Chiara Damiani3,4,5,+,*
E-mail: f.lapi@campus.unimib.it
1 Centro Nacional de Análisis Genómico, Barcelona, Spain.
2 Immunobiology Department, Yale School of Medicine, New Haven, USA
3 Department of Biosciences and Biotecnologies, University of Milano-Bicocca, Milan, IT
4 Institute of bioimaging and complex biological systems (IBSBC), Segrate, IT
5 SYSBIO Centre of Systems Biology/ ISBE.IT
6 National Biodiversity Future Center (NBFC)
7 Department of Oncology, KU Leuven, Leuven, Belgium
8 Universitat de Barcelona (UB), Barcelona, Spain
9 Department of Informatics, Systems and Communication, University of Milano-Bicocca, Milan, IT
x These authors contributed equally
+ Senior authors
* Corresponding author

Keywords: Cancer metabolism, Reverse Warburg effect, Tumor microenvironment, Spatial transcriptomics, Spatial Flux Balance Analysis

#BtBsDay - #BtBsDayST10

ST10_ABSTRACT SHORT TALK_Lapi Francesco

ST11_How Light-Controlled FUS Aggregation Can Help Model ALS/FTD

Speaker - Eugeni Alessandra

Alessandra Eugeni¹, Nadia Buchendorfer¹², Silvia Lombardi¹, Roland Nicsanu¹, Silvia Maria Luisa Barabino¹
E-mail: alessandra.eugeni@unimib.it
¹ Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
² Faculty of Biology, University of Barcelona, Spain

Keywords: FUS, ALS, aggregation, optogenetics, Cry2olig, phase separation

#BtBsDay - #BtBsDayST11

ST11_ABSTRACT SHORT TALK_Eugeni Alessandra

ST12_IL-22BP expression by a specialized cDC2 subset shapes anti-tumor immunity in the colonic microenvironment

Speaker - Celant Anna

Anna Celant1, Giuseppe Rocca1, Marco Galli1, Stefano Cozzi1, Valentina Melocchi2, Francesca Colnaghi1, Francesca Bono3, Fabrizio Bianchi2, Laura Marongiu1, Metello E. Innocenti1, Francesca Granucci1
E-mail: anna.celant@unimib.it
1 Università degli Studi di Milano-Bicocca, Italia
2 Casa Sollievo della Sofferenza IRCCS, Italia
3 Fondazione San Gerardo IRCCS, Italia

Keywords: dendritic cells, colitis-associated colon cancer, T cell responses

#BtBsDay - #BtBsDayST12

ST12_ABSTRACT SHORT TALK_Celant Anna_RESERVED_Confidential Information

BtBsDay2026 Graphical Abstracts (GA01-GA15)

Giornata del Dipartimento di Biotecnologie e Bioscienze 2026

Programma BtBsDay 2026

Graphical Abstracts - Galleria delle Scienze

GA01_Characterization and comparative analysis of the effects of Artemisia abrotanum, Artemisia annua and Artemisia vulgaris on colorectal cancer cell lines

Graphical abstract presenter - Martini Gaia

Gaia Martini 1 , Federica Bovio1, Stefano Bianchini1, Stefano Negri2,3, Flavia Guzzo2,3, Matilde Forcella1,3, Paola Fusi1,3
E-mail: g.martini13@campus.unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza dellaScienza 2, 20126 Milano, Italy.
2 Department of Biotechnology, University of Verona, Strada Le Grazie 15, 37134 Verona, Italy.
3 National Biodiversity Future Center (NBFC), 90133 Palermo, Italy.

Keywords: Colorectal cancer, Artemisia, apoptosis, cell cycle, oxidative stress, autophagy

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GA01_ABSTRACT GRAPHICAL ABSTRACT_Martini Gaia

GA02_Butterfly effect: infrastructures and tools to connect biodiversity and society via pollination services

Graphical abstract presenters - Brambilla Giulia & Galassini Andrea

Brambilla Giulia1 & Galassini Andrea A. R.1, Meeus I.2, Biella P.1
E-mail: g.brambilla48@campus.unimib.it & a.galassini@campus.unimib.it
1 Università degli Studi di Milano-Bicocca, Milano, Italia.
2 University of Ghent, Ghent, Belgium.

Keywords: pollinators, biodiversity, ecosystem services, urbanization, agricultural landscape, supporting tools

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GA02_ABSTRACT GRAPHICAL ABSTRACT_Brambilla Giulia & Galassini Andrea

GA03_Biomimetic responsive antigen-delivery vehicles for therapeutic and preventive vaccines against hereditary triple-negative breast cancer

Graphical abstract presenter - Banfi Andrea

Andrea Banfi1, Stefania Garbujo1, Davide Prosperi1, Miriam Colombio1
E-mail: a.banfi17@campus.unimib.it
1 NanoBioLab, Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.

Keywords: triple negative breast cancer, biomimetic nanoparticles, adaptive immunity, vaccinology

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GA03_ABSTRACT GRAPHICAL ABSTRACT_Banfi Andrea

GA04_Synthetic biology approach for the valorisation of caffeic acid in S. cerevisiae

Graphical abstract presenter - Fontana Ginevra

Stefano Bertacchi,a,b Ginevra Fontana,c Giovanni Maria Bernardini,a Lorenzo Guzzetti,a,b Davide Sala,a Massimo Labra,a,b Paola Branduardi a,b,*
E-mail: stefano.bertacchi@unimib.it
a Department of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy
b NBFC – National Biodiversity Future Center, 90133 Palermo, Italy
c Department of Medical Biotechnology and Translational Medicine, University of Milano, 20122, Milan, Italy

Keywords: Saccharomyces cerevisiae, caffeic acid, synthetic biology, genetic engineering, biosensors

#BtBsDay - #BtBsDayGA04

GA04_ABSTRACT GRAPHICAL ABSTRACT_Fontana Ginevra

GA05_A natural compound ameliorates hepatic steatosis through regulation of lipid metabolism in vitro

Graphical abstract presenter - Sanguedolce Andrea

Andrea Sanguedolce1, Hind Moukham1, Giorgia Spandri1 Valentina Santoro2,3, Anna Lisa Piccinelli2, Farida Tripodi1,2, Paola Coccetti1,2
E-mail: a.sanguedolce1@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, Italy
2National Biodiversity Future Center (NBFC), Palermo, Italy.
3Department of Pharmacy, University of Salerno, Fisciano, Italy

Keywords: Natural compounds, NAFLD, lipid metabolism, lipophagy, lipolysis, AMPK, PKA

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GA05_ABSTRACT GRAPHICAL ABSTRACT_Sanguedolce Andrea

GA06_Neuronal differentiation induced by thermal stimulation: the role of possible candidate ion channels

Graphical abstract presenter - Cuttica Camilla

Camilla Cuttica1, Martina Mariani1, Alessia D’Aloia1,2, Sarah Placida1, Alessia Metallo1, Marzia Lecchi1
E-mail: c.cuttica@campus.unimib.it
1 Department of Biotechnology and Biosciences, University of Milano – Bicocca2 Center for Genomic Science of IIT@SEMM, Istituto Italiano di Tecnologia (IIT), Milan, Italy

Keywords: neuroblastoma cell line, thermal stimulation, neuronal differentiation, electrical activity, immunocytochemical analysis, functional analysis, temperature-sensitive channels

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GA06_ABSTRACT GRAPHICAL ABSTRACT_Cuttica Camilla

GA07_Active-Site Modeling and Molecular Dynamics Characterization of CelOCE, a Copper Polysaccharide-Degradating Enzyme

Graphical abstract presenter - Fumagalli Gioele

Gioele Fumagalli1, Lara Callea2, Luca Bertini1, Luca De Gioia1, Federica Arrigoni1
E-mail: g.fumagalli69@campus.unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca
2 Department of Earth and Environmental Sciences, University of Milano-Bicocca

Keywords: CelOCE, Cu(II) active site, Molecular Dynamics (MD), Polysaccharide degradation, Active-site Dynamics, Cellulose

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GA07_ABSTRACT GRAPHICAL ABSTRACT_Fumagalli Gioele

GA08_Development and optimization of functional nanomaterials for physical modulation of cell aging processes

Graphical abstract presenter - Benedetti Daniele

Daniele Benedetti1,2, Francesco Lodola1,2, Maria Rosa Antognazza2
E-mail: d.benedetti5@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2,20126 Milano, Italy
2 Center for Nano Science and Technology@PoliMi, Istituto Italiano di Tecnologia, Via Raffaele Rubattino81, 20134 Milano, Italy

Keywords: aging, skin aging, light, nanomaterials, nanoparticles.

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GA08_ABSTRACT GRAPHICAL ABSTRACT_Benedetti Daniele

GA09_A novel optoelectronic platform combining LED-driven pacing and laser optoporation for high-throughput cardiac electrophysiology

Graphical abstract presenter - Distefano Enide

Enide Distefano1, Claudia Maniezzi2, Antonio Zaza2, Michele Dipalo3, Chiara Florindi2 and Francesco Lodola2
E-mail: eni.distefano@gmail.com
1 Department of Biology and Biotechnology, University of Pavia, Pavia, Italy
2Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
3FORESEE Biosystems Srl, Genova, Italy

Keywords: Laser poration, cardiomyocytes, high-throughput analysis

#BtBsDay - #BtBsDayGA09

GA09_ABSTRACT GRAPHICAL ABSTRACT_Distefano Enide

GA10_Plant-derived extracts against neurodegenerative disorders: an integrated workflow to characterize their anti-amyloidogenic properties

Graphical abstract presenter - Miccichè Maria

Maria Miccichè1, Linda Molteni1, Luca Moretti1, Maura Brioschi1, Alessandro Palmioli1,2, Cristina Airoldi1,2
E-mail: m.micciche5@campus.unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2 NeuroMI, Milan Center for Neuroscience, University of Milano-Bicocca, 20126 Milano, Italy.

Keywords: Amyloid, Natural Extracts, NMR, MS, CD, FTIR, AFM

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GA10_ABSTRACT GRAPHICAL ABSTRACT_Miccichè Maria

GA11_Delivery of Curcumin-Loaded Polymeric Nanoparticles in Granulates for Oral Administration

Graphical abstract presenter - Valer Zanabria Gabriela Paola

Gabriela Paola Valer Zanabria1, E. Ochoa1, M. Colombo1, D. Prosperi1, M. Giustra1
E-mail: g.valerzanabria@campus.unimib.it
1NanoBioLab, Department of Biotechnology and Biosciences, Università degli Studi di Milano-Bicocca, Italy

Keywords: Delivery, polymeric nanoparticles, curcumin, oral solid dosage form

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GA11_ABSTRACT GRAPHICAL ABSTRACT_Valer Zanabria Gabriela Paola

GA12_Discovering PITX2 Gain-of-Function Effects associated to atrial fibrillation in Patient-Derived cardiomyocytes

Graphical abstract presenter - Zeppellini Giorgia_RESERVED_Confidential Information

Arici M.1, Zeppellini G.1, Zaccaria R.1, Metallo A. 1, Benzoni P.2, Rocchetti M.1
E-mail: g.zeppellini@campus.unimib.it
1Dept. of Biotechnology and Biosciences. University of Milano-Bicocca, Milan Italy
2Dept. of Biosciences. University of Milano. Milan, Italy

Keywords: PITX2, atrial fibrillation, calcium handling, mitochondria, sarcoplasmic reticulum

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GA12_ABSTRACT GRAPHICAL ABSTRACT_Zeppellini Giorgia_RESERVED_Confidential Information

GA13_Eco-Sustainable Nanoparticles Production Using Green Solvents

Graphical abstract presenter - Gelosa Carla Giulia_RESERVED_Confidential Information

Carla Giulia Gelosa1, Miriam Colombo1, Davide Prosperi1, Marco Davide Giustra1
E-mail: c.gelosa1@campus.unimib.it
1NanoBioLab, Department of Biotechnology and Biosciences, University of Bicocca Milan, Italy

Keywords: Green solvents, Eco-sustainability, Polymeric Nanoparticles

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GA13_ABSTRACT GRAPHICAL ABSTRACT_Gelosa Carla Giulia_RESERVED_Confidential Information

GA14_Towards a Microbiome-Inclusive Climate Agenda: A Graphical Abstract for the World Microbiome Partnership

Graphical abstract presenter - Ghisleni Giulia_RESERVED_Confidential Information

Giulia Ghisleni1
E-mail: giulia.ghisleni@unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca

Keywords: Microbiome; Climate change; Nature-based Solutions

#BtBsDay - #BtBsDayGA14

GA14_ABSTRACT GRAPHICAL ABSTRACT_Ghisleni Giulia_RESERVED_Confidential Information

GA15_Micro- and Nanoplastics Are Everywhere: Impact on Intestinal Inflammation and Brain Health

Graphical abstract presenters - Motto Martina & Rella Anastasia

Anastasia Rella1*, Martina Motto1*, Ameen-Ur Rashid2,3, Alessandro Galli1, Zana Meta1, Silvia Valtorta3,4, Sara Belloli3,4, Rosa Maria Moresco3,4,5, Anna Maria Colangelo1
E-mail: anastasia.rella@unimib.it, m.motto1@campus.unimib.it
1Dept of Biotechnology and Biosciences, University of Milano Bicocca;
2PhD program in Neuroscience, Medicine andSurgery Department, University Milano-Bicocca, Monza;
3Nuclear Medicine Dept, San Raffaele Scientific Institute(IRCSS), Milano;
4CNR-IBSBC, Segrate;
5Dept of Medicine and Surgery, University of Milano-Bicocca, Monza.
*These authors contributed equally

Keywords: Plastics, Intestine, Inflammation, Neurotoxicity

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GA15_ABSTRACT GRAPHICAL ABSTRACT_Motto Martina & Rella Anastasia