The research area in Biomedicine focuses on studying the cellular and molecular mechanisms underlying various human diseases, with an approach aimed at understanding the biological dynamics of pathological conditions. Research lines include oncology, neurodegenerative, cardiovascular, genetic, and inflammatory diseases, as well as dysbiosis, to investigate how molecular circuits and cellular signaling pathways are altered in pathological and preclinical conditions. The goal is to identify new diagnostic markers and pharmacological targets, as well as to develop preventive pharmacological or nutraceutical strategies to counteract disease development.

The area also includes advanced studies in nanomedicine, focusing on the development of nanoparticles and biomaterials for targeted applications in oncology and regenerative medicine. The systems biology approach enables an integrated analysis of cellular and molecular networks, providing a comprehensive view of molecular interactions in pathological conditions and potential therapeutic strategies.

With a strong emphasis on biotechnological innovation and interdisciplinarity, the Biomedicine research area of the Department aims to generate knowledge applicable to personalized and precision medicine and nutrition.

•    Advanced Cell Models for Biomedicine - Group Leader: Luisa Fiandra
•    Cardiac Cell Physiology - Group Leader: Antonio Zaza
•    Cardiovascular Cell Physiology - Group Leader: Marcella Rocchetti 
•    Cell Pathobiology and Molecular Therapy - Group Leader: Metello Innocenti
•    Cell Physiology and Neurophysiology - Group Leader: Andrea Becchetti
•    Cellular and Molecular Biology - Group Leader: Michela Ceriani
•    Cellular and Molecular Immunology - Group Leader: Francesca Granucci
•    Cellular and Molecular Physiology - Group Leader: Francesco Lodola
•    Developmental Neuroimmunobiology - Group Leader: Veronica Krenn
•    Food Microbiology and Probiotic Science (μbEat lab) - Group Leader: Simone Guglielmetti
•    Genetics of Neurodevelopment and its Pathology - Group Leader: Silvia K. Nicolis
•    Genome Damage - Group Leader: Michela Clerici
•    Genome Integrity and Stability - Group Leaders: Maria Pia Longhese and Diego Bonetti
•    Laboratory of Neuroscience "Rita Levi-Montalcini" - Group Leader: Anna Maria Colangelo
•    Molecular Genetics of Hematopoiesis - Group Leader: Antonella Ronchi
•    Mucosal Immunology - Group Leader: Federica Facciotti
•    NanoBioLab + NanoCosPha - Group Leaders: Davide Prosperi and Miriam Colombo
•    Neural Development - Group Leader: Sara Mercurio
•    Pharmacology & Drug discovery - Group Leader: Barbara Costa
•    Physiology of Neuronal Differentiation - Group Leader: Marzia Lecchi
•    RNA Biology - Group Leader: Silvia Barabino
•    Stem Cells and Clinical Translation in Neuroscience - Group Leader: Daniela Ferrari
•    Systems Biochemistry of Cancer Cell Metabolism and Proliferation - Group Leaders: Marco Vanoni and Elena Sacco
•    Tumor Biochemistry - Group Leader: Ferdinando Chiaradonna