room 1016, building U3, tel. +39 02 6448 3052

lab 5040, building U4, tel. +39 02 6448 3514

veronica.krenn@unimib.it

see also: ResearcherID (publons), ORCID, Linkedin,  Twitter, Scopus

Cascio Anna – Postgraduate Fellow
lab 5040, building U4, tel. +39 02 6448 3514
anna.cascio@unimib.it

Veronica Krenn graduated cum Laude in Biotechnologies at the University of Milano-Bicocca, Italy, and received a PhD in Molecular Medicine at the University of Milano, with an internship at the Institute of Experimental Oncology (IEO), working on human mitotic division in the Musacchio laboratory.

She moved to the Max-Planck Insitute of Molecular Physiology in Germany during her PhD and later to the Knoblich laboratory at the Vienna BioCenter as Post-Doc, where she started to work on human brain organoid systems. She joined our department in 2022, after being awarded with the Early Career Fellowship promoted by the Human Technopole.

Brain development, cerebral organoids, iPSCs, microglia, neuroinflammation, genetic diseases, congenital infections

The lab uses stem cells - derived models to investigate the molecular basis of neuroimmune interactions regulating brain development and their alterations in disease conditions

-A human organoid-based culture of Central nervous system-Associated Macrophages (CAM) for functional study of -neurodevelopment and disease
Anno: 2023
Bando: FAQC 2023 - prima finestra
Enti finanziatori: Università degli Studi di MILANO-BICOCCA

-Human Neuroimmunobiology Project - The project aims at developing human stem cells- derived 2D and 3D cellular models to study the mechanisms of neuroimmunological dysfunction and their contribution to the pathogenesis of neurodevelopmental disorders.
Anno: 2021
Enti finanziatori: FONDAZIONE HUMAN TECHNOPOLE

-Krenn, V., Bosone, C., Burkard, T.R., Spanier, J., Kalinke, U., Calistri, A., Salata, C., Rilo Christoff, R., Pestana Garcez, P., Mirazimi, A., Knoblich, J.A. 2021 Organoid modeling of Zika and herpes simplex virus 1 infections reveals virus-specific responses leading to microcephaly. Cell Stem Cell 28, 1362–1379.e7. doi:10.1016/j.stem.2021.03.004

-Bajaj, S., Bagley, J.A., Sommer, C., Vertesy, A., Nagumo Wong, S., Krenn, V., Lévi-Strauss, J., Knoblich, J.A., 2021. Neurotransmitter signaling regulates distinct phases of multimodal human interneuron migration. EMBO J. 40, e108714. doi:10.15252/embj.2021108714

National collaborations:

Prof. Silvia Nicolis, Università degli Studi di Milano-Bicocca (UNIMIB)

Prof. Giuseppe Testa, Human Technopole

International collaborations:

Prof. Jürgen Knoblich, IMBA -Vienna

Dr. Christopher Esk, University of Innsbruck

Krenn’s Lab – #KrennLab_BtBs
last update June 2022

Elenco non esaustivo ed in continuo aggiornamento.

fonte: pagina web Progetti di ricerca d’Ateneo

MULTIvalent and MULTIfunctional MODulators of Enzyme activity: towards multi-target drugs (Multi-Mode)

Anno: 2022
Bando: FAQC 2022 - prima finestra
Responsabili: LA FERLA BARBARA

Role of AMPK in atrIaL agE-dependent arrhythmogeneSis predisposiTiOn: insigths from humaN and mousE models (MILESTONE)

Anno: 2022
Bando: FAQC 2022 - prima finestra
Responsabili: ROCCHETTI MARCELLA

Advanced Nanotechnology to Assist Keeping the tumor microenvironment Involved in cancer Neutralization (ANAKIN) - I annualità

Anno: 2021
Bando: Investigator Grant - IG 2021
Responsabili: COLOMBO MIRIAM

AGRO2CIRCULAR - Territorial Circular Systemic Solution for the upcycling of residues from the agrifood sector

Anno: 2021
Bando: Demonstration of systemic solutions for the territorial deployment of the circular economy
Responsabili: BRANDUARDI PAOLA

Biodiversità Funzionale Del Vivaio Bicocca

Anno: 2021
Responsabili: LABRA MASSIMO

Brain gene regulation in 3D: long-range promoter-enhancer functional interaction networks in mouse and human brain cells, and their relevance for neurodevelopmental disease

Anno: 2021
Bando: FAQC 2021 - prima finestra
Responsabili: NICOLIS SILVIA KIRSTEN

Deciphering the heterogeneity of dendritic cells in human non-small cell lung cancer - III annualità

Anno: 2021
Bando: AIRC Investigator Grant (IG) 2019
Responsabili: GRANUCCI FRANCESCA

Exploiting DNA damage response protein O-glycosylation to enhance chemotherapy in pancreatic cancer

Anno: 2021
Bando: FAQC 2021 - prima finestra
Responsabili: CHIARADONNA FERDINANDO

Human Neuroimmunobiology

Anno: 2021
Responsabili: GRANUCCI FRANCESCA , KRENN VERONICA

NUOVI FARMACI PER COVID-19: PIATTAFORME PER LO SCREENING "HIGH-THROUGHPUT" DI COMPOSTI

Anno: 2021
Bando: FAQC 2021 - terza finestra
Responsabili: LODOLA FRANCESCO

Search for plastic-degrading enzymes in plastisphere microbial communities from the Gulf on Naples (PLAZY)

Anno: 2021
Bando: FAQC 2021 - terza finestra
Responsabili: LOTTI MARINA

Seguridad Alimentaria Sostenible en el Occidente de El Salvador: agroecología, empoderamiento, participación e innovación

Anno: 2021
Responsabili: BRUNI ILARIA

Supramolecular assemblies in cell invasion as targets for cancer therapy

Anno: 2021
Bando: FAQC 2021 - terza finestra
Responsabili: BROCCA STEFANIA

Targeting DNA double-strand break repair in cancer: genetic and biochemical approaches to study DNA end resection - V annualità

Anno: 2021
Bando: 2017-005 - Call for Proposals 2017 Investigator Grant (IG)
Responsabili: LONGHESE MARIA PIA

Understanding dyserythropoiesis to identify new therapeutic mechanisms in hereditary anemias

Anno: 2021
Bando: Decreto Direttoriale n.1628 del 16-10-2020 - Bando PRIN 2020
Responsabili: RONCHI ANTONELLA ELLENA

Preclinical evaluation of a PGM3 inhibitor as innovative therapeutic approach for pancreatic ductal adenocarcinoma – Terza annualità

Anno: 2021
Responsabili: CHIARADONNA FERDINANDO