Seminario - Biotecnologie e Bioscienze - Giovedì 27 marzo 2025, ore 16:30, edificio BIOS-U3, aula U3-04 e Webex
Biophysics Week 2025 Affiliate Event
-BPS Bulletin (May 2025). Celebrating 10 Years of Biophysics Week!
-Biophysics Week Seminar at the UNIMIB
William Louch, University of Oslo, Norway
Abstract
Contraction of the heart is reliant on the shortening of individual cardiomyocytes, elicited by Ca2+ release at sub-cellular structures called dyads. However, the precise arrangement and function of dyads remains unclear, both in health and disease. Our work has examined this critical question using emerging microscopy techniques, including live-cell super-resolution (PALM) imaging. Our results show that nanoscale changes in dyadic structure promote fine-tuning of Ca2+ release in health, but deranged Ca2+ homeostasis during heart failure. These data suggest that newfound regulators of dyadic structure and function may serve as novel therapeutic targets in this disease.
Ospite: Antonio Zaza, Francesco Lodola
Il seminario sarà trasmesso anche in streaming su Webex:
https://unimib.webex.com/unimib-it/j.php?MTID=m361b4ee63abdc8da55337e9dcb010325
Password: day27
Il seminario è APERTO a tutti.