Dipartimento di Biotecnologie e Bioscienze BtBs
room 3052, building U3, tel. +39 02 6448 3368
lab 3013/2014, building U3, tel. +39 02 6448 3365/3366
Ferrari’s Lab – #FerrariLab_BtBs
last update: September 2020
The READy project is being carried on by a regional scientific network of excellence for the rapid response to bio-emergencies. The project is aimed at developing new bioreagents and diagnostic kits that target emerging tropical diseases, i.e., Chagas disease, arbovirus-related diseases (Dengue, Chikungunya, Zika), malaria and schistosomiasis. For this purpose, proteins must be isolated and purified from several microorganisms, such as Trypanosoma cruzi, Plasmodium SPP, Schistosoma SPP, Dengue, Chikungunya, e Zika.
room 5014, building U4, tel. +39 02 6448 3510
Zanoni’s Lab – #ZanoniLab_BtBs
last update: August 2020
-ZAMPELLA-Fondo per il finanziamento delle attività base di ricerca
Anno: 2017
Bando: FFABR 2017
Enti finanziatori: M.I.U.R. - MINISTERO DELL'ISTRUZIONE, DELL'UNIVERSITA' E DELLA RICERCA - UFFICIO I - Bilancio e Contabilita'. Coordinamento staff della Direzione
Panzeri, D., Toini, E., Vertemara, J., Silvestri, G., Bunea, V., Zecca, G., et al. (2024). Small proteins, great promises: geographic bioprospecting of Bowman-Birk protease Inhibitors and domestication side-effects in African cowpea (Vigna unguiculata L.). PLANTS, PEOPLE, PLANET, 6(4 (July 2024)), 921-934 [10.1002/ppp3.10507].
Ami, D., Santambrogio, C., Vertemara, J., Bovio, F., Santisteban-Veiga, A., Sabín, J., et al. (2024). The Landscape of Osteocalcin Proteoforms Reveals Distinct Structural and Functional Roles of Its Carboxylation Sites. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 146(40), 27755-27769 [10.1021/jacs.4c09732].
Silvestri, G., Arrigoni, F., Persico, F., Bertini, L., Zampella, G., De Gioia, L., et al. (2023). Assessing the Performance of Non-Equilibrium Thermodynamic Integration in Flavodoxin Redox Potential Estimation. MOLECULES, 28(16) [10.3390/molecules28166016].
Arrigoni, F., De Gioia, L., Elleouet, C., Pétillon, F., Schollhammer, P., Talarmin, J., et al. (2023). Normal vs. Inverted Ordering of Reduction Potentials in [FeFe]-Hydrogenases Biomimetics: Effect of the Dithiolate Bulk. CHEMISTRY-A EUROPEAN JOURNAL, 29(38 (July 6, 2023)), 1-12 [10.1002/chem.202300569].
Zampella’s Lab – #ZampellaLab_BtBs
last update: April 2025
room 5017, building U4, tel. +39 02 6448 3522
lab 5044, building U4, tel. +39 02 6448 3534
Vertemara Jacopo – PostDoc
room 4064, building U3, tel. +39 02 6448 3473, jacopo.vertemara@unimib.it
-Signal transduction
-Computational Biology
-Systems Biology
-Biological systems analysis, modelling and simulation
-Marsella A, Gobbini E, Cassani C, Tisi R, Cannavo E, Reginato G, Cejka P, Longhese MP. Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners. Cell Rep. 2021 Mar 30;34(13):108906. doi: 10.1016/j.celrep.2021.108906.
-Tisi R, Spinelli M, Palmioli A, Airoldi C, Cazzaniga P, Besozzi D, Nobile MS, Mazzoleni E, Arnhold S, De Gioia L, Grandori R, Peri F, Vanoni M, Sacco E. The Multi-Level Mechanism of Action of a Pan-Ras Inhibitor Explains its Antiproliferative Activity on Cetuximab-Resistant Cancer Cells. Front Mol Biosci. 2021 Feb 17;8:625979. doi: 10.3389/fmolb.2021.625979.
-Tisi R, Gaponenko V, Vanoni M, Sacco E. Natural Products Attenuating Biosynthesis, Processing, and Activity of Ras Oncoproteins: State of the Art and Future Perspectives. Biomolecules. 2020 Nov 10;10(11):1535. doi: 10.3390/biom10111535.
-Tisi R, Vertemara J, Zampella G, Longhese MP. Functional and structural insights into the MRX/MRN complex, a key player in recognition and repair of DNA double-strand breaks. Comput Struct Biotechnol J. 2020 May 16;18:1137-1152. doi: 10.1016/j.csbj.2020.05.013.
Tisi’s Lab – #TisiLab_BtBs
last update May 2021
Italian Delegate for the Life Science division of the European Chemical Society
President of the MicrobiotaMi association
Rector's Delegate for the Foundation University for Innovation U4i
room 4047, building U3, tel. +39 02 6448 3453
lab 4048, building U3, tel. +39 02 6448 3455
-TArgeting antimicrobial resistance by LEad optimization and Nanoformulation of innovative anTibiotics and efflux pumps inhibitors (TALENT)
Anno: 2023
Bando: FAQC 2023 - seconda finestra
Enti finanziatori: Università degli Studi di MILANO-BICOCCA
-PNRR per la Missione 4, componente 2 Investimento 1.1- Avviso 104/2022 | TENET – Targeting bacterial cell ENvelope to reverse rEsisTance in emerging pathogens
Anno: 2022
Bando: Bando PRIN 2022
Enti finanziatori: MINISTERO DELL'UNIVERSITA' E DELLA RICERCA (MUR)
-Alagia, M., Bengoechea, C., La Ferla, B., Peri, F., Guerrero, A. (2025). Effects of the green cross-linking agent tannic acid and its oxidation on the properties of porcine plasma protein superabsorbent materials. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 304(Part 1 ( April 2025)) [10.1016/j.ijbiomac.2025.140584].
-Franco, A., Aladailleh, Z., Romerio, A., Italia, A., Lami, F., Shaik, M., et al. (2025). Towards more efficient synthetic immunomodulators: biological characterization and mechanism of action of monosaccharide-derived TLR4 agonists. RSC MEDICINAL CHEMISTRY [10.1039/D4MD00950A].
-Alagia, M., La Ferla, B., Zoia, L., Peri, F. (2025). Renewable proteins from agricultural and animal sources as innovative multifunctional bio-fillers for rubber composites: A comprehensive review. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 284(Part 1 (January 2025)) [10.1016/j.ijbiomac.2024.137941].
-Ami, D., Franco, A., Artusa, V., Romerio, A., Shaik, M., Italia, A., et al. (2024). Vibrational spectroscopy coupled with machine learning sheds light on the cellular effects induced by rationally designed TLR4 agonists. TALANTA, 275(1 August 2024) [10.1016/j.talanta.2024.126104].
Peri’s Lab – #PeriLab_BtBs
last update: April 2025
room 3047, building U3, tel. +39 02 6448 3347
lab 3040, building U3, tel. +39 02 6448 3040
Blasa Stefania - PostDoc
lab 3041/3047, building U3, tel. +39 02 6448 3311/3347, stefania.blasa@unimib.it
Nanomedicine and Biomaterials, Neurodegenerative and neurological diseases, Stem cells and Regenerative Medicine
Physiological mechanisms underlying neuronal differentiation induced by scalable thermal stimulation
Lecchi’s Lab – #LecchiLab_BtBs
last update September 2020
