BtBs seminario - Nanodynamo quantifies the dynamics of RNA metabolism and unravels extensive coupling between steps of the RNA life cycle

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Mattia Pelizzola, Department of Biotechnology and Biosciences, University of Milano‐Bicocca - giovedì 19 ottobre, 2023, ore 16:30, edificio Tellus (ex U4), aula U4-03 / Webex

Seminario - Biotecnologie e Bioscienze - giovedì 19 ottobre, 2023, ore 16:30, edificio Tellus (ex U4) aula U4-03 / Webex

Mattia Pelizzola, Department of Biotechnology and Biosciences, University of Milano‐Bicocca

Abstract

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Seminari BtBs UNIMIB

The coordinated action of transcriptional and post-transcriptional machineries shapes gene expression programs. We developed Nanodynamo, an experimental and computational workflow for quantifying the kinetic rates of nuclear and cytoplasmatic steps of the RNA life cycle. We revealed pervasive post-transcriptional RNA processing. We unraveled coupling between transcriptional, processing, export, decay and translational machineries, which largely contribute to coordinating how cells respond to perturbations that impact gene expression programs.

 

 

Document

LINK per partecipare al seminario: https://unimib.webex.com/unimib-it/j.php?MTID=m4061398cd4ae89de2ed64044acf51c79

password:  day19 (32919 da telefoni e sistemi video)

Il seminario è APERTO a tutti.

tag:   #BtBsSeminars , #PelizzolaLab_BtBs

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