UniStem Day
Conoscere e innovare: l'infinito viaggio della ricerca scientifica
Dipartimento di Biotecnologie e Bioscienze BtBs
seminario - Immunopathogenesis of psoriatic disease
Giovedì 21 marzo 2019, ore 12:00, aula 2025, edificio U3
Ferrari Daniela, PhD
Assistant Professor in Applied Biology
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room 3052, building U3, tel. +39 02 6448 3368
lab 3013/2014, building U3, tel. +39 02 6448 3365/3366
Ferrari’s Lab – #FerrariLab_BtBs
last update: September 2020
READy project
The READy project is being carried on by a regional scientific network of excellence for the rapid response to bio-emergencies. The project is aimed at developing new bioreagents and diagnostic kits that target emerging tropical diseases, i.e., Chagas disease, arbovirus-related diseases (Dengue, Chikungunya, Zika), malaria and schistosomiasis. For this purpose, proteins must be isolated and purified from several microorganisms, such as Trypanosoma cruzi, Plasmodium SPP, Schistosoma SPP, Dengue, Chikungunya, e Zika.
Area di ricerca: BIOMEDICINA
Immagine Slide
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Sottotitolo
i gruppi di ricerca coinvolti
Peso
2
La Spettrometria di massa per la ricerca scientifica
La Spettrometria di Massa per la ricerca scientifica: approcci targeted e untargeted nello studio di small molecules
Metabolic characterization of maturing human pluripotent stem cell-derived cardiomyocytes
Giulia Emanuelli – Cardiovascular School, King’s College, London
Zanoni Ivan, PhD
Associate Professor
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room 5014, building U4, tel. +39 02 6448 3510
Zanoni’s Lab – #ZanoniLab_BtBs
last update: August 2020
Zampella Giuseppe
Associate Professor of General and Inorganic Chemistry
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Research projects
-ZAMPELLA-Fondo per il finanziamento delle attività base di ricerca
Anno: 2017
Bando: FFABR 2017
Enti finanziatori: M.I.U.R. - MINISTERO DELL'ISTRUZIONE, DELL'UNIVERSITA' E DELLA RICERCA - UFFICIO I - Bilancio e Contabilita'. Coordinamento staff della Direzione
Publications
Panzeri, D., Toini, E., Vertemara, J., Silvestri, G., Bunea, V., Zecca, G., et al. (2024). Small proteins, great promises: geographic bioprospecting of Bowman-Birk protease Inhibitors and domestication side-effects in African cowpea (Vigna unguiculata L.). PLANTS, PEOPLE, PLANET, 6(4 (July 2024)), 921-934 [10.1002/ppp3.10507].
Ami, D., Santambrogio, C., Vertemara, J., Bovio, F., Santisteban-Veiga, A., Sabín, J., et al. (2024). The Landscape of Osteocalcin Proteoforms Reveals Distinct Structural and Functional Roles of Its Carboxylation Sites. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 146(40), 27755-27769 [10.1021/jacs.4c09732].
Silvestri, G., Arrigoni, F., Persico, F., Bertini, L., Zampella, G., De Gioia, L., et al. (2023). Assessing the Performance of Non-Equilibrium Thermodynamic Integration in Flavodoxin Redox Potential Estimation. MOLECULES, 28(16) [10.3390/molecules28166016].
Arrigoni, F., De Gioia, L., Elleouet, C., Pétillon, F., Schollhammer, P., Talarmin, J., et al. (2023). Normal vs. Inverted Ordering of Reduction Potentials in [FeFe]-Hydrogenases Biomimetics: Effect of the Dithiolate Bulk. CHEMISTRY-A EUROPEAN JOURNAL, 29(38 (July 6, 2023)), 1-12 [10.1002/chem.202300569].
Zampella’s Lab – #ZampellaLab_BtBs
last update: April 2025
Tisi Renata Anita, PhD
Associate Professor in Molecular Biology
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room 5017, building U4, tel. +39 02 6448 3522
lab 5044, building U4, tel. +39 02 6448 3534
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Research group
Vertemara Jacopo – PostDoc
room 4064, building U3, tel. +39 02 6448 3473, jacopo.vertemara@unimib.it
Keywords
Homology modelling; Small molecule-protein docking; Protein-protein docking
Research areas
-Signal transduction
-Computational Biology
-Systems Biology
-Biological systems analysis, modelling and simulation
Selected publications
-Marsella A, Gobbini E, Cassani C, Tisi R, Cannavo E, Reginato G, Cejka P, Longhese MP. Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners. Cell Rep. 2021 Mar 30;34(13):108906. doi: 10.1016/j.celrep.2021.108906.
-Tisi R, Spinelli M, Palmioli A, Airoldi C, Cazzaniga P, Besozzi D, Nobile MS, Mazzoleni E, Arnhold S, De Gioia L, Grandori R, Peri F, Vanoni M, Sacco E. The Multi-Level Mechanism of Action of a Pan-Ras Inhibitor Explains its Antiproliferative Activity on Cetuximab-Resistant Cancer Cells. Front Mol Biosci. 2021 Feb 17;8:625979. doi: 10.3389/fmolb.2021.625979.
-Tisi R, Gaponenko V, Vanoni M, Sacco E. Natural Products Attenuating Biosynthesis, Processing, and Activity of Ras Oncoproteins: State of the Art and Future Perspectives. Biomolecules. 2020 Nov 10;10(11):1535. doi: 10.3390/biom10111535.
-Tisi R, Vertemara J, Zampella G, Longhese MP. Functional and structural insights into the MRX/MRN complex, a key player in recognition and repair of DNA double-strand breaks. Comput Struct Biotechnol J. 2020 May 16;18:1137-1152. doi: 10.1016/j.csbj.2020.05.013.
Tisi’s Lab – #TisiLab_BtBs
last update May 2021