Biotechnology and Biosciences Seminar - giovedì 24 febbraio, 2022, ore 16:30, aula U3-04 / Webex
Farida Tripodi, Assistant Professor of Biochemistry at University of Milano-Bicocca (Department of Biotechnology and Biosciences)
Abstract

Robust biological systems are able to adapt to internal and environmental perturbations. This is ensured by a thick crosstalk between metabolism and signal transduction pathways, through which cell cycle progression, metabolism and growth are coordinated. Cell signaling strongly controls metabolism, mainly through transcriptional regulation and post-translational modifications. Strikingly, also metabolism regulates signal transduction, acting through protein-metabolite interactions (PMIs), which result in the modification of protein activities. Our laboratory has long been involved in the study of these cross-regulations, especially focusing on the yeast protein kinase AMPK. It is a highly conserved key enzyme in all eukaryotic cells, essential for energy homeostasis and adaptation to glucose limitation. I will discuss our findings on AMPK regulation on cell cycle and metabolism and its crosstalk with other signaling pathways in the model organism Saccharomyces cerevisiae.
LINK per partecipare al seminario: https://unimib.webex.com/unimib-it/j.php?MTID=m1301eba85bb5568b20c855829a19a69c
password: day03 (32903 da telefoni)
Il seminario è APERTO a tutti.
tag: #BtBsSeminars #TripodiLab_BtBs
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