BtBs Seminar - Neural stem cells: from initial discovery to clinical trials for neurological disorders

Prof. Angelo Vescovi,

Professor of Cell Biology - Department of Biotechnology and Biosciences, UNIMIB
Director of Research - IRCCS Casa Sollievo della Sofferenza & Inst. Human Genetics G.Mendel
Full Affiliate Professor of  Neurology - Houston Methodist Institute for Academic Medicine, USA
Founder  and Chief Strategic Officer  - StemGen Spa, Italy and HyperStem SA, Lugano, CH
Ordinary Member - Pontifical Academy for Life, State of Vatican City

The dogma that the mammalian brain was incapable of neurogenesis in adulthood was initially challenged in the early sixties by Joseph Altman, whom proposed that new neural cells could be generated within discrete areas of the adult central nervous system. The seminar describes an ideal journey, beginning with the initial discovery of the persistence of active neurogenic precursors in the adult mouse telencephalon in the early 90s in Calgary, during my postdoctoral training, through the demonstration that such cells were, indeed neural stem cells and the isolation of their human counterpart from the fetal brain a few years later in Milan. A discussion will follow as to the most relevant physiological properties of these cells and how these were harnessed to establish standardized cell therapy drugs and implement successful phase I trials for Multiple Sclerosis, ALS and for incurable glioblastoma in humans, recently concluded.

LINK per partecipare al seminario:  https://unimib.webex.com/unimib-it/j.php?MTID=mc3a87eb98ec084a1f72f5ec4bed56094

password:   day10 (32910 da telefoni)

Il seminario è APERTO a tutti.

tag:   #BtBsSeminars  #VescoviLab_BtBs

Gli attestati di partecipazione al seminario sono validi anche per l’acquisizione dei CFU, per altre informazioni e richiesta, visitare il link dedicato.