BtBsDay2026 Short talks (ST01-ST12)

Giornata del Dipartimento di Biotecnologie e Bioscienze 2026

Programma BtBsDay 2026

Short Talks - Sironi room (U4-08)

ST01_Inhibition of the Hexosamine Biosynthetic Pathway Impairs PIKK Maturation and Induces a BRCAness-Like Phenotype in Triple-Negative Breast Cancer

Speaker - Taverna Gabriele

Gabriele Taverna1, Barbara Zerbato1, Giulia Monterosso1, Eleonora Foti1, Ester Gallo1, Cinzia Bragato2, Lorenzo Taglietti2, Barbara La Ferla2, Domenica Scumaci3, Ferdinando Chiaradonna1.
E-mail: gabriele.taverna@unimib.it
1Milano-Bicocca University, department of Biotechnology and Bioscience – BTBS, Italy.
2Milano-Bicocca University, department of Earth and Environmental Science – DISAT, Italy
3Magna Graecia University of Catanzaro, department of Experimental and Clinic Medicine – DMSC, Italy

Keywords: Breast cancer, HBP, FR054, ATM, ATR, DNA-PK, BRCA1, Zebrafish.

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ST01_ABSTRACT SHORT TALK_Taverna Gabriele

ST02_Different Lenses, Same Target: NMR Spectroscopy and Other Biophysical Tools for the Comprehensive Characterization of Prenylflavonoids Anti-Amyloidogenicity

Speaker - Molteni Linda

Linda Molteni1, Chiara Bruzzone1, Diletta Ami1,2, Ada De Luigi3, Laura Colombo3, Luca Moretti1, Antonino Natalello1,2, Alessandro Palmioli1,2, Cristina Airoldi1,2
E-mail: l.molteni@campus.unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, P.zza della Scienza 2, 20126 Milan, Italy.
2 NeuroMI, Milan Center for Neuroscience, University of Milano-Bicocca, 20126 Milano, Italy.
3 Department of Molecular Biochemistry and Pharmacology - Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via M. Negri 2, 20156 Milano, Italy.

Keywords: Xanthohumol, Aβ1-42, NMR, FTIR, AFM

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ST02_ABSTRACT SHORT TALK_Molteni Linda

ST03_Harnessing Mirror-Image Peptides: Nanoparticle Vectors for Nucleic Acid Delivery in Cancer Treatment

Speaker - Banfi Andrea

Andrea Banfi1, Lucia Salvioni1, Miriam Colombo1, Davide Prosperi1
E-mail: a.banfi17@campus.unimib.it
1 NanoBioLab, Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy

Keywords: peptide-based nanoparticles, targeted therapy, nucleic acids nanodelivery, immunotherapy, cancer

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ST03_ABSTRACT SHORT TALK_Banfi Andrea

ST04_A natural modulator of the PKA and AMPK signaling regulates lipid metabolism in a steatosis model

Speaker - Moukham Hind

Hind Moukham¹, Andrea Sanguedolce¹, Giorgia Spandri¹, Alessia Lambiase¹², Valentina Santoro²³, Anna Lisa Piccinelli²³, Farida Tripodi¹², Paola Coccetti¹²
E-mail: h.moukham@campus.unimib.it
¹Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, Italy
²National Biodiversity Future Center (NBFC), Palermo, Italy
³Department of Pharmacy, University of Salerno, Fisciano, Italy

Keywords: NAFLD, Flavonoids, Lipolysis, Lipohagy, Lipid droplets, HepG2 cells, signaling

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ST04_ABSTRACT SHORT TALK_Moukham Hind

ST05_Cellular consequences of non-ablative radiotherapy, a novel approach to ventricular tachycardias

Speaker - Maniezzi Claudia

Claudia Maniezzi1, Stefano Busti1, Angela S. Maione2, Elena Sommariva2, Francesco P. Cammarata3, Giusi I. Forte3, Gaetano M. De Ferrari4, Francesco Lodola1, Antonio Zaza1
E-mail: claudia.maniezzi@unimib.it
1 University of Milano-Bicocca, Milan, Italy
2 Unit of Inherited Cardiomyopathies, Centro Cardiologico Monzino IRCCS, Milan, Italy
3 Institute of Bioimaging and Complex Biological Systems, National Research Council, Cefalù, Italy &National Institute for Nuclear Physics, Laboratori Nazionali del Sud, Catania, Italy
4 Unit of Cardiology, Department of Medical Sciences, University of Turin, Turin Italy & Division ofCardiology, Molinette Hospital, Città della Salute e della Scienza, Turin, Italy

Keywords: non-ablative radiotherapy, Na+ current, ROS, CaMKII

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ST05_ABSTRACT SHORT TALK_Maniezzi Claudia

ST06_From Cells to Circuits: Ethical Challenges and Opportunities in 3Rs-Aligned Modeling of Sleep Disorders

Speaker - Grandi Laura Clara

Laura Clara Grandi1,2, Francesca Gullo1, Andrea Becchetti1
E-mail: laura.grandi@unimib.it
1 Dipartimento di Biotecnologie e Bioscienze, Università di Milano Bicocca, Milano, Italia
2 Dipartimento di medicina sperimentale e clinica, Università degli studi di Firenze, Firenze, Italia

Keywords: Narcolepsy, Epilepsy, Sleep disorders, 3Rs, Animal models, Neuronal cultures, Brain slices, Translational neuroscience

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ST06_ABSTRACT SHORT TALK_Grandi Laura Clara

ST07_HCN4 misregulation affects the early differentiation process of mouse embryonic stem cells

Speaker - Arici Martina

Martina Arici1, V. Pastori1, P. Benzoni2, R. Pensotti1, A. Metallo1, A. Ronchi1, M. Rocchetti1
E-mail: martina.arici@unimib.it
1 University of Milano-Bicocca, Italy
2 University of Milano, Italy

Keywords: HCN4, differentiation, pacemaker channel, mESC, cardiac development

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ST07_ABSTRACT SHORT TALK_Arici Martina_RESERVED_Confidential Information

ST08_Electrochemical and computational methods as a combined approach to study redox enzymes

Speaker - Fasano Andrea

Andrea Fasano1, Federica Arrigoni1, Lara Callea1, Vincent Fourmond2, Luca Bertini1, Christophe Léger2, Luca de Gioia1
E-mail: andrea.fasano@unimib.it
1 Department of Biotechnology and Biosciences, University of Milan-Bicocca, Milan, 20126, Italy
2 Laboratoire de Bioénergétique et Ingénierie des Protéines CNRS, Aix Marseille Université, Marseille13402, France

Keywords: Redox enzymes; O2 inhibition; Quantum mechanics; Protein film electrochemistry

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ST08_ABSTRACT SHORT TALK_Fasano Andrea

ST09_The university campus microbiome: ecological drivers of skin–gut–environment microbial interactions

Speaker - Ghisleni Giulia

Giulia Ghisleni1, Alice Armanni1, Sara Fumagalli1, Jessica Zampolli1, Patrizia Di Gennaro1*, Antonia Bruno1*
E-mail: giulia.ghisleni@unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca

Keywords: Microbiome; Human–environment interactions; Skin microbiome; Gut microbiome; Built environment; Urbanization; University microbiome; 16S rRNA gene sequencing

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ST09_ABSTRACT SHORT TALK_Ghisleni Giulia

ST10_Spatial Flux Balance analysis reveals Warburg heterogeneity in renal tumors and lactate-consuming niches in colorectal cancer

Speaker - Lapi Francesco

Davide Maspero1,x , Giovanni Marteletto2,x, Francesco Lapi3,x, Bruno G. Galuzzi4,5,6, Irene Ruano1 , Ben Vandenbosch7, Ke Yin7, Sabine Tejpar7, Alex Graudenzi9, Holger Heyn1,8 , Anna Pascual-Reguant1,+ , Chiara Damiani3,4,5,+,*
E-mail: f.lapi@campus.unimib.it
1 Centro Nacional de Análisis Genómico, Barcelona, Spain.
2 Immunobiology Department, Yale School of Medicine, New Haven, USA
3 Department of Biosciences and Biotecnologies, University of Milano-Bicocca, Milan, IT
4 Institute of bioimaging and complex biological systems (IBSBC), Segrate, IT
5 SYSBIO Centre of Systems Biology/ ISBE.IT
6 National Biodiversity Future Center (NBFC)
7 Department of Oncology, KU Leuven, Leuven, Belgium
8 Universitat de Barcelona (UB), Barcelona, Spain
9 Department of Informatics, Systems and Communication, University of Milano-Bicocca, Milan, IT
x These authors contributed equally
+ Senior authors
* Corresponding author

Keywords: Cancer metabolism, Reverse Warburg effect, Tumor microenvironment, Spatial transcriptomics, Spatial Flux Balance Analysis

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ST10_ABSTRACT SHORT TALK_Lapi Francesco

ST11_How Light-Controlled FUS Aggregation Can Help Model ALS/FTD

Speaker - Eugeni Alessandra

Alessandra Eugeni¹, Nadia Buchendorfer¹², Silvia Lombardi¹, Roland Nicsanu¹, Silvia Maria Luisa Barabino¹
E-mail: alessandra.eugeni@unimib.it
¹ Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
² Faculty of Biology, University of Barcelona, Spain

Keywords: FUS, ALS, aggregation, optogenetics, Cry2olig, phase separation

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ST11_ABSTRACT SHORT TALK_Eugeni Alessandra

ST12_IL-22BP expression by a specialized cDC2 subset shapes anti-tumor immunity in the colonic microenvironment

Speaker - Celant Anna

Anna Celant1, Giuseppe Rocca1, Marco Galli1, Stefano Cozzi1, Valentina Melocchi2, Francesca Colnaghi1, Francesca Bono3, Fabrizio Bianchi2, Laura Marongiu1, Metello E. Innocenti1, Francesca Granucci1
E-mail: anna.celant@unimib.it
1 Università degli Studi di Milano-Bicocca, Italia
2 Casa Sollievo della Sofferenza IRCCS, Italia
3 Fondazione San Gerardo IRCCS, Italia

Keywords: dendritic cells, colitis-associated colon cancer, T cell responses

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ST12_ABSTRACT SHORT TALK_Celant Anna_RESERVED_Confidential Information

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