room 5065, building U3, tel. +39 02 6448 3363

lab 2i42, building U3, tel. +39 02 6448 3392

carlo.santambrogio@unimib.it

Structural biology; Protein conformational ensemble; Protein-protein & protein-ligand interaction; Intrinsically disordered proteins; Amyloid aggregation; Proteomics; Mass spectrometry; Biochemical and biophysical methods

Nanomedicine and biomaterials; Neurodegenerative and neurological diseases; Molecular modeling and structural biology

Santambrogio’s Lab - #SantambrogioLab_BtBs
last update March 2020

room 4050, building U3, tel. +39 02 6448 3459

lab 4051, building U3, tel. +39 02 6448 3461

see also (inserire l’url o ID): PudMed, ResearchGate, Google Scholar, Scopus,  ORCID

antonino.natalello@unimib.it

Amyloids, Bioanalytical Methods, Biophysics, FTIR Micro-spectroscopy, FTIR spectroscopy, Intact-cell Spectroscopy, Lipids, Protein Aggregation, Protein Stability, Spectroscopy.     

Ami Diletta – PostDoc Fellow

room 4051/4050, IV floor, building U3, tel: +39 02 6448 3461/3459, diletta.ami@unimib.it

Lopez Arriz Martin Antonio – Master student

room 4051, IV floor, building U3, tel: +39 02 6448 3461, m.lopezarriz@campus.unimib.it

-Protein folding, misfolding and aggregation in vitro and in situ studied by biophysical approaches, including infrared spectroscopy and micro-spectroscopy, optical spectroscopies (absorption, florescence, circular dichroism), and mass spectrometry. Major research topics: 1) protein stability; 2) amyloid aggregation; 3) structure-function relation; 4) aggregation of recombinant proteins; 5) protein-protein and protein-ligand interactions; 6) nano- and bio-materials.

-Bioanalytical applications of spectroscopic methods. Major research topics: FTIR (micro)spectroscopy of complex biological systems; in situ studies of biological processes; spectroscopic markers of neurodegenerative disorders in biofluids.  

RITESSERE. Silk Sericin materials from textile industry by-products
Anno: 2023
Enti finanziatori: FONDAZIONE CARIPLO

-Sala BM, Le Marchand T, Pintacuda G, Camilloni C, Natalello A, Ricagno S. Conformational Stability and Dynamics in Crystals Recapitulate Protein Behavior in Solution. Biophys J. 2020; 119(5):978-988. doi: 10.1016/j.bpj.2020.07.015.

-Ami D, Mereghetti P, Foli A, Tasaki M, Milani P, Nuvolone M, Palladini G, Merlini G, Lavatelli F, Natalello A. ATR-FTIR Spectroscopy Supported by Multivariate Analysis for the Characterization of Adipose Tissue Aspirates from Patients Affected by Systemic Amyloidosis. Anal Chem. 2019; 91(4):2894-2900. doi: 10.1021/acs.analchem.8b05008.

-Ami D, Lavatelli F, Rognoni P, Palladini G, Raimondi S, Giorgetti S, Monti L, Doglia SM, Natalello A, Merlini G. In situ characterization of protein aggregates in human tissues affected by light chain amyloidosis: a FTIR microspectroscopy study. Sci Rep. 2016; 6:29096. doi: 10.1038/srep29096.

-Natalello A, Mangione PP, Giorgetti S, Porcari R, Marchese L, Zorzoli I, Relini A, Ami D, Faravelli G, Valli M, Stoppini M, Doglia SM, Bellotti V, Raimondi S. Co-fibrillogenesis of Wild-type and D76N β2-Microglobulin: THE CRUCIAL ROLE OF FIBRILLAR SEEDS. J Biol Chem. 2016;291(18):9678-89. doi: 10.1074/jbc.M116.720573.

Natalello’s Lab – #NatalelloLab_BtBs
last update: May 2021

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To add this calendar to your Google Calendar:

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room 3052, building U3, tel. +39 02 6448 3368

lab 3013/2014, building U3, tel. +39 02 6448 3365/3366

daniela.ferrari@unimib.it

Ferrari’s Lab – #FerrariLab_BtBs
last update: September 2020