room 3014, building U3, tel. +39 02 6448 3228

lab 3015, building U3, tel. +39 02 6448 3331

lab 3050, building U3, tel. +39 02 6448 3316

francesco.lodola@unimib.it

see also: ResearchGate, Google Scholar, Scopus, ResearchID, ORCID, loop

Chiara Florindi, PhD Student (XXXVIII Ciclo)
Lab 3015 (tel. +39 6448 3331), building U3
Lab 3050 (tel. +39 6448 3316), building U3
c.florindi@campus.unimib.it

Francesca Misitano, PhD Student (XXXIX Ciclo)
Lab 3015 (tel. +39 6448 3331), building U3
Lab 3050 (tel. +39 6448 3316), building U3
f.misitano@campus.unimib.it

Ludovica Cestariolo, Assegnista  
Lab 3015 (tel. +39 6448 3331), building U3
Lab 3050 (tel. +39 6448 3316), building U3
ludovica.cestariolo@unimib.it

Cardiovascular Physiology, Ca²⁺ signaling, Excitation-contraction coupling, Arrhythmias, Optical stimulation, Nanomaterials, Nanomedicine. 

Ca²⁺ signaling and cardiac arrhythmias; Novel optics-based approaches for cardiac electrophysiology.

-PRIN 2022 PNRR- Missione 4, Componente 2, Investimento 1.1 -Avviso 1409/22 - Interaction between myofilament and SERCA2a activators on heart muscle mechanics
Anno: 2022
Bando: Bando PRIN 2022
Enti finanziatori: M.I.U.R. - MINISTERO DELL'ISTRUZIONE, DELL'UNIVERSITA' E DELLA RICERCA

-NUOVI FARMACI PER COVID-19: PIATTAFORME PER LO SCREENING "HIGH-THROUGHPUT" DI COMPOSTI
Anno: 2021
Bando: FAQC 2021 - terza finestra
Enti finanziatori: Università degli Studi di MILANO-BICOCCA

*Co-first author, #Corresponding author

[1] C. Maniezzi, M. Eskandr, C. Florindi, M. Ferrandi, P. Barassi, E. Sacco, V. Pasquale, A.S. Maione, G. Pompilio, V.O.N. Teixeira, R.A. de Boer, H.H.W. Silljé, F. Lodola#, A. Zaza, Early consequences of the phospholamban mutation PLN‐R14del+/− in a transgenic mouse model, Acta Physiologica (2024). DOI: 10.1111/apha.14082

[2] V. Vurro, B. Federici, C. Ronchi, Florindi C., V. Sesti, S. Crasto, Maniezzi C., Galli C., M.R. Antognazza, C. Bertarelli, E.D. Pasquale, Lanzani G., F. Lodola#, Optical modulation of excitation-contraction coupling in human induced pluripotent stem cell-derived cardiomyocytes, iScience (2023). DOI: 10.1016/j.isci.2023.106121

[3] M.L. DiFrancesco, F. Lodola*, E. Colombo, L. Maragliano, M. Bramini, G.M. Paternò, P. Baldelli, M.D. Serra, L. Lunelli, M. Marchioretto, G. Grasselli, S. Cimò, L. Colella, D. Fazzi, F. Ortica, V. Vurro, C.G. Eleftheriou, D. Shmal, J.F. Maya-Vetencourt, C. Bertarelli, G. Lanzani, F. Benfenati, Neuronal firing modulation by a membrane-targeted photoswitch, Nature Nanotechnology (2020). DOI: 10.1038/s41565-019-0632-6

[4] F. Lodola#, V. Vurro, S. Crasto, E. Di Pasquale, G. Lanzani Optical Pacing of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Mediated by a Conjugated Polymer Interface. Advanced Healthcare Materials (2019). DOI: 10.1002/adhm.201900198

Prof. Guglielmo Lanzani and Dr. Maria Rosa Antognazza - Istituto Italiano di Tecnologia

Prof. Kevin Kit Parker - Harvard University

Prof.ssa Chiara Bertarelli and Prof. José Félix Rodriguez Matas - Politecnico di Milano

Prof. Giulio Pompilio - Centro Cardiologico Monzino

Prof.ssa Cecilia Ferrantini - Università di Firenze

Lodola’s Lab – #LodolaLab_BtBs
last update: March 2024

room 4008/4019, building U4, tel. +39 02 6448 3330

luca.campone@unimib.it,

Campone’s Lab – #CamponeLab_BtBs
last update November 2020

room 4024, building U3, tel.: +39 02 6448 3308

pasquale.palumbo@unimib.it

Laurea degree (1995) and Ph.D (2000) in Electronic Engineering, University of L’Aquila. Associate Professor of Automatic Control (ING/INF-04), Department of Biotechnologies and Biosciences, University of Milano-Bicocca, since 2019.

In 2000 joined the Institute of Systems Analysis and Computer Science “A. Ruberti” at the National Research Council (IASI-CNR) as a post-doc till 2005, then as a reasearcher till 2019, then as a research associate till present. In 2019 won a CNR contest as a senior researcher.

Contract Professor at the University of L’Aquila, School of Engineering, from 2000 till 2019, teaching Probability and Statistics (2000/01 and 2001/02), Automatic Control (2002/03), Systems Theory (from 2003/04 till 2006/07), Systems Biology (lessons in English, 2018/19). Supervisor of more than 80 theses (36 Master theses) concerning Systems Theory, Automatic Control, Biomathematics and Systems Biology.

Honorary Professor at Obuda University, Budapest, Hungary (since 2018).

Member of the IEEE Control Systems Society and of the IEEE Technical Committees on Systems Biology and on Healthcare and Medical Systems. Member of the Italian Association of Researchers in Automatic Control (SIDRA). Member of the Italian Society for Applied and Industrial Mathematics (SIMAI). Member of the Italian Society of Biochemistry and Molecular Biology (SIB).

Author of over 100 peer-review publications, indexed on ISI-WOS and Scopus. Recipient of the 2013 Editor's Award of the Kybernetyka Journal. Recipient of the 2018 Editor's Award of the IET Systems Biology Journal.

Member of the Editorial Board of PLoS ONE, Frontiers, Mathematical Problems in Engineering journals. Member of the Conference Editorial Board (CEB) of the IEEE Control Systems Society

Mathematical Control Theory, State estimation, Nonlinear Filtering, Stochastic Systems, Artificial Pancreas, Healthcare and Biomedical Systems, Systems Biology, Synthetic Biology, Chemical Master Equations

Scientific activity involves both methodological items, like Mathematical control theory (Polynomial method for stochastic control and filtering, Positive systems) and application items, like Mathematical modeling and control in biology and medicine (glucose-insulin models, the artificial pancreas, tumor growth control) and Systems and Synthetic Biology (Integrated models of cellular metabolism, growth and cycle, Metabolic Flux Analysis, Chemical Master Equations, noise propagation in transcriptional and metabolic networks)

-Formal Methods for the design of an Artificial Pancreas for subjects with type 2 diabetes and clinical validation
Anno: 2023
Bando: FAQC 2023 - seconda finestra
Enti finanziatori: Università degli Studi di MILANO-BICOCCA

(1) Palumbo, P., Vanoni, M., Cusimano, V., Busti, S., Marano, F., Manes, C., et al. (2016). Whi5 phosphorylation embedded in the G 1 /S network dynamically controls critical cell size and cell fate. NATURE COMMUNICATIONS, 7, 11372.

(ii) Borri, A., Palumbo, P., & Singh, A. (2016). Impact of negative feedback in metabolic noise propagation. IET SYSTEMS BIOLOGY, 10(5), 179-186.

(iii) Borri, A., Cacace, F., De Gaetano, A., Germani, A., Manes, C., Palumbo, P., et al. (2017). Luenberger-Like Observers for Nonlinear Time-Delay Systems with Application to the Artificial Pancreas: The Attainment of Good Performance. IEEE CONTROL SYSTEMS, 37(4), 33-49.

(iv) Cacace, F., Cusimano, V., & Palumbo, P. (2020). Optimal impulsive control with application to antiangiogenic tumor therapy. IEEE TRANSACTIONS ON CONTROL SYSTEMS TECHNOLOGY, 28(1), 106-117.

National Research Council (CNR)

Obuda University

University of L’Aquila

University of Delaware

Vrije University Amsterdam

Campus Bio-Medico University of Rome

Palumbo’s Lab – #PalumboLab_BtBs
last update September 2020