Research area: Biomedicine

WORK IN PROGRESS

Keywords: Advanced cell models, drug discovey, nanomedicine, preclinical studies, biological barriers, murine models, zebrafish, optical and electron microscopy.

• Preclinical in vitro e in vivo studies, and development of advanced cellular 3D models, for the validation of conventional or latest generation drugs directed towards tumor or neurodegenerative pathologies;
• Validation of nanoformulated systems for drug delivery across biological barriers (eg. BBB, skin);
• Study of the toxicity of nanomaterials and nanodrugs on 2D/3D in vitro and in vivo experimental models, and in zebrafish.
• Studies aimed to the implementation of electron microscopy systems, through the subcellular localization of different types of nanoparticles.

Fiandra Luisa - Group Leader

luisa.fiandra@unimib.it
room 3014, building U3, tel.: +39 02 6448 3406
lab 4015, building U4, tel. +39 02 6448 3440
see also: Scopus 7801514947 , Orcid, Linkedin
BtBs profile, UNIMIB profile , Publications (IRIS – Institutional Research Information System)

-Rosini Benedetta  - studente tesi magistrale
laboratorio 4015, edificio U3, tel. +39 02 6448 3406, b.rosini@campus.unimib.it

Bengalli R, Colantuoni A, Perelshtein I, Gedanken A, Collini M, Mantecca P, Fiandra L.
In vitro skin toxicity of CuO and ZnO nanoparticles: Application in the safety assessment of antimicrobial coated textiles. NanoImpact Volume 21, January 2021, 100282. DOI: 10.1016/j.impact.2020.100282

Bellini M, Riva B, Tinelli V, Rizzuto MA, Salvioni L, Colombo M, Mingozzi F, Visioli A, Marongiu L, Frascotti G, Christodoulou MS, Passarella D, Prosperi D, Fiandra L.
Engineered Ferritin Nanoparticles for the Bioluminescence Tracking of Nanodrug Delivery in Cancer. Small 2020, 28: e2001450. DOI: 10.1002/smll.202001450

Das P, Fatehbasharzad P, Colombo M, Fiandra L, Prosperi D.
Multifunctional Magnetic Gold Nanomaterials for Cancer. Trends Biotechnol. 2019 Sep;37(9):995-1010. doi: 10.1016/j.tibtech.2019.02.005

Colombo M*, Fiandra L*, Alessio G, Mazzucchelli S, Nebuloni M, De Palma C, Kantner K,  Pelaz B, Corsi F, Parak WJ, Prosperi D.
Tumour homing and therapeutic effect of colloidal nanoparticles depend on the number of attached antibodies. Nat Commun. 2016 Dec 19;7:13818. doi: 10.1038/ncomms13818.

Fiandra’s Lab – #FiandraLab_BtBs
last update: April 2025