BtBsDay2025 Poster session (P61-P70)

Giornata del Dipartimento di Biotecnologie e Bioscienze 2025

Programma BtBsDay 2025

Poster session - Galleria della Scienza (U3-U4)

P61 - Mechanoreceptors initiate innate immunity in response to microbial infections

Poster presenter – Giulia Stucchi

Giulia Stucchi1, Laura Marongiu1, Giuseppe Rocca1, Marco Galli1, Anna Celant1, Stefano Cozzi1, Martina Molgora1, Alessandra Polissi2, Alessandra Maria Martorana2, Marina Vai1, Ivan Orlandi1, Metello Enzo Innocenti1, Francesca Granucci1,
E-mail: giulia.stucchi@unimib.it
1 University of Milano-Bicocca, Italy
2 University of Milan, Italy

Keywords: Innate immunity, microbial sensing, tissue mechanosensing

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P61_ABSTRACT POSTER_Stucchi Giulia

P62 - PhosphoDJ1: Disclosing a novel link between epigenetic dysregulation and breast cancer

Poster presenter – Gabriele Taverna

Gabriele Taverna1, Marina La Chimia2, Cristina Fontana2, B. Zerbato1, Cristian Scatena3, Ferdinando Chiaradonna1, Domenica Scumaci2
E-mail: g.taverna5@campus.unimib.it
1Dpt. of Biotechnology and Biosciences, University of Milano Bicocca, Piazza della Scienza 2, Milano, Italy
2Dpt. of Experimental and Clinical Medicine, Magna Græcia University of Catanzaro, Viale S. Venuta, Catanzaro, Italy
3Dpt. of Laboratory Medicine, Pisa University Hospital, Anatomia Patologica 1 Universitaria, Pisa, Italy.

Keywords: Glycolysis, MGO, Histone glycation, DJ-1, DNA damage, DNA repair, O-Glycosylation, chemoresistance

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P62_ABSTRACT POSTER_Gabriele Taverna

P63 - Which plants would you choose to study for new drug discovery? A pipeline for a phylogenetic approach

Poster presenter – Elisa Toini

Elisa Toini1,2, Giovanni Zecca1,2, Maria Totaro1,3, Massimo Labra1,2, Fabrizio Grassi1,2
E-mail: e.toini@campus.unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza Della Scienza 2,20126 Milan, Italy
2 NBFC, National Biodiversity Future Center, 90133 Palermo, Italy
3 Faculty of Education, Free University of Bozen-Bolzano, Brixen-Bressanone, Italy

Keywords: phylogenetic methods, medicinal plant, drug discovery

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P63_ABSTRACT POSTER_Toini Elisa

P64 - Sema3A RNA nanodelivery to pancreatic ductal adenocarcinoma microenvironment for the activation of tumor immune response

Poster presenter – Giulia Tomaino

Giulia Tomaino1, Elena Guerrini1, Lucia Salvioni1, Stefania Garbujo1, Luisa Fiandra1, Metello Innocenti1, Davide Prosperi1
E-mail: giulia.tomaino@unimib.it
1 Università degli Studi di Milano Bicocca, Italia

Keywords: PDAC, Tumor microenvironment, Semaphorin, LNPs, mRNA delivery, Endothelium on-a-chip

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P64_ABSTRACT POSTER_Tomaino Giulia

P65 - Study of Bowman-Birk inhibitors (BBIs) in the genus Vigna (Fabaceae) and their binding affinity with trypsin and chymotrypsin

Poster presenter – Maria Totaro

Maria Totaro1,2, Elisa Toini1,3, Jacopo Vertemara1, Giuseppe Silvestri1, Giovanni Zecca1,3, Robert Wagensommer2, Massimo Labra1,3, Fabrizio Grassi1,3
E-mail: maria.totaro@unibz.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2 Faculty of Education, Free University of Bozen-Bolzano, Brixen-Bressanone, Italy
3 NBFC, National Biodiversity Future Center, 90133 Palermo, Italy

Keywords: BBIs, proteins, binding affinity

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P65_ABSTRACT POSTER_Totaro Maria

P66 - Qualitative behavior analysis and identification issues of generalized Lotka-Volterra models of microbial communities

Poster presenter – Matteo Turati

Matteo Turati1, Patrizia Di Gennaro1, Pasquale Palumbo1, Margherita Finazzi1
E-mail: m.turati14@campus.uimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, Italy

Keywords: Generalized Lotka-Volterra (gLV) model, Ecological stability, Microbial communities

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P66_ABSTRACT POSTER_Turati_Matteo

P67 - Exploring the optimization of polyethylene biodegradation by Rhodococcus opacus R7 through its degradative enzymatic systems

Poster presenter – Valentina Vincenti

Zampolli J.1, Vincenti V.1, Veronelli G.1, Mangiagalli M.1, Lotti M.1, Ami D1, Natalello A.1, Bertini L.1, Arrigoni F.1, Di Gennaro P.1
E-mail: v.vincenti1@campus.unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, Italy

Keywords: Rhodococcus genus, polyethylene, plastic-degrading enzymes, multicopper oxidases, laccases, oxygenases, lipases

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P67_ABSTRACT POSTER_Vincenti Valentina

P68 - Exploring the metabolic signature of Amyotrophic Lateral Sclerosis patientsderived cells

Poster presenter – Edvige Vulcano

Vulcano Edvige1, Perciballi Elisa 4, Lombardi Ivan1, Carletti Rose Mary6, Bovio Federica1, Matilde Forcella1, Rosati Jessica6, Gelati Maurizio4, Profico Daniela4, Fusi Paola1, Vescovi Angelo Luigi 6,7, Ferrari Daniela1
E-mail: e.vulcano@campus.unimib.it
1 Department of Biotechnology and Biosciences, University of Milano-Bicocca, Italy;
4 Fondazione IRCCS Casa Sollievo della Sofferenza, Institute for Stem-Cell Biology, Regenerative Medicine and Innovative Therapies (ISBReMIT), San Giovanni Rotondo, Italy;
6 Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy;
7 Link Campus University, Rome, Italy.

Keywords:

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P68_ABSTRACT POSTER_Vulcano Edvige

P69 - A Non-Canonical Tricarboxylic Acid Cycle Underlying Cellular Identity: An In Silico Perspective

Poster presenter – Lihao Lin

Lihao Lin1, Fabiola Maria Andrea Saputo1 , Francesco Lapi1, Isabella Cecilia Rizzo1, Bruno Giovanni Galuzzi2, Marco Ercole Vanoni1, Chiara Damiani1
E-mail: l.lin6@campus.unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy
2 CNR Centro Nazionale delle Ricerche, Segrate (Milan), Italy

Keywords: Metabolic Modeling; Non-canonical Krebs cycle; ENGRO2 computational model

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P69_ABSTRACT POSTER_Lihao Lin

P70 - Mechanism of Snf1/AMPK autoregulation linked to subcellular localization in Saccharomyces cerevisiae

Poster presenter – Hind Moukham

Hind Moukham1, Farida Tripodi1, Giorgia Spandri1, Alessia Lambiase1, Marco Caligaris2, Raffaele Nicastro2, Claudio De Virgilio2, Paola Coccetti1
E-mail: hind.moukham@unimib.it
1Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, Italy.
2Department of Biology, University of Fribourg, Fribourg, Switzerland.

Keywords: Snf1/AMPK, budding yeast, metabolic stress, subcellular localization

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P70_ABSTRACT POSTER_Hind Moukham

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