Seminar - Biotechnology and Biosciences - Thursday, February 1, 2024, 4:30 p.m., U3-BIOS building, room U3-01 / Webex
Cintia Roodveldt, CABIMER-Center for Molecular Biology & Regenerative Medicine, University of Seville, Spain
Abstract
Neuroinflammation is an early feature in Amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases and microglial neurotoxic responses are considered to have a key role in disease onset and progression. However, the mechanisms underlying dysregulated microglial activation and inflammatory responses remain incompletely understood. We have recently revealed that MOK kinase plays a role in CNS immunity by controlling microglial responses that involve epigenetic mechanisms. Moreover, recent results uncover other MOK-supported signalling pathways. Importantly, based on our results from studies with a preclinical model, we propose that MOK has a role in the pathophysiology of ALS.
Host: Daniela Ferrari
LINK to participate in the seminar: https://unimib.webex.com/unimib-it/j.php?MTID=maedc28c0e20c75458ae9aeecf469a48c
password: day01 (32901 da telefoni e sistemi video)
The seminar is OPEN to everyone.
tag: #BtBsSeminars , #FerrariLab_BtBs