BtBs Seminar - Bioactive and biomimetic nanotherapeutics to modulate inflammation and immune response

Ennio Tasciotti - giovedì 6 ottobre, 2022, ore 16:30, edificio TELLUS, aula U4-02 / Webex

Biotechnology and Biosciences Seminar - giovedì 6 ottobre, 2022, ore 16:30, edificio TELLUS, aula U4-02 / Webex

Dr. Ennio Tasciotti, PhD – Director Human Longevity Program, IRCCS San Raffaele Rome, Full Professor Biotechnology, San Raffaele University

Abstract

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Seminari-BtBs-UNIMIB

Recent advances in the field of nanomedicine have shown that biomimicry strategies can be employed to improve targeting properties while simultaneously enabling nanocarriers with a biological identity to better interact with the surrounding microenvironment. Immune cells in particular employ membrane proteins to target inflamed vasculature, locally increase vascular permeability, extravasate across inflamed endothelium, and regulate local and systemic inflammation. Inspired by the physiology of immune cells, we developed a procedure to transfer leukocyte surface proteins onto nanoparticles and demonstrated their cross-talk with the endothelium and the different cells populating the microenvironment of target tissues.

LINK per partecipare al seminario:  https://unimib.webex.com/unimib-it/j.php?MTID=m6445e968782a91b86328c5dacc67d8ab

password:  day06 (32906 da telefoni)

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