Biotechnology and Biosciences Seminar - giovedì 9 giugno, 2022, ore 16:30, aula U3-04 / Webex
Francesco Strati, Assistant Professor in General Pathology at University of Milano-Bicocca, Department of Biotechnology and Biosciences
Abstract
The gut microbiota is a master regulator of host physiology. Intestinal microbes produce numerous metabolites through primary and secondary metabolic pathways, many of which are dependent on host diet. The effects exerted by these microbial-derived metabolites represent therefore the combined output of host-microbe interactions influencing host energy metabolism, development and function of the immune system, maintenance of mucosal integrity as well as intestinal microbiota community dynamics.
I will discuss the current knowledge on specific microbial-derived metabolites, notably secondary bile acids, short chain fatty acids and tryptophan metabolites, and their role in affecting host health. Furthermore, I will show how microbiota-derived metabolites induce the production of the anti-inflammatory cytokine IL10 by iNKT cells, a population of tissue resident unconventional T lymphocytes, promoting intestinal homeostasis and control of inflammation in experimental colitis models.
LINK per partecipare al seminario: https://unimib.webex.com/unimib-it/j.php?MTID=md17e52605aaa4ab65844ad080816419e
password: day09 (32909 da telefoni)
Il seminario è APERTO a tutti.
tag: #BtBsSeminars #StratiLab_BtBs
Gli attestati di partecipazione al seminario sono validi anche per l’acquisizione dei CFU, per altre informazioni e richiesta, visitare il link dedicato.