Call text in Italian and English https://www.unimib.it/ateneo/gare-e-concorsi/assegni-ricerca-tipo-a2-a2-type-research-grants-2021
For any information: marina.lotti@unimib.it , Lotti’s Lab
Psychrophilic organisms adapted to cold environments produce molecules of relevance for biotechnological application, in particular enzymes active at low temperatures and ice-binding proteins that control the growth of ice crystals. The use of cold-active enzymes supports low temperature processes that preserve heat labile compounds and can result, in some circumstances, in energy saving and are therefore or interest for application in the food, biotransformation and bioremediation sector. The goal of this project deals with the discovery of novel cold-active enzymes, with the production thereof as recombinant proteins and with improvement of performances by protein engineering and other techniques. Particular emphasis is on structure-function relationships as unveiled by structural and conformational analysis.