The READy project is being carried on by a regional scientific network of excellence for the rapid response to bio-emergencies. The project is aimed at developing new bioreagents and diagnostic kits that target emerging tropical diseases, i.e., Chagas disease, arbovirus-related diseases (Dengue, Chikungunya, Zika), malaria and schistosomiasis. For this purpose, proteins must be isolated and purified from several microorganisms, such as Trypanosoma cruzi, Plasmodium SPP, Schistosoma SPP, Dengue, Chikungunya, e Zika. The unit at the University of Milano-Bicocca is at present carrying on the purification and characterization of proteins from Plasmodium (vivax and falciparum), i.e., MSP-1 and CSP, to be employed in immunological assays for the detection of antibodies in patients and blood products.
Funding
Regione Lombardia (2017-2020) PI – Prof. Paolo Tortora
Other units involved in the projects:
- Dia. Pro Diagnostic Bioprobes Srl (Company, project coordinator), Dr. Edoardo Marchisio
- Consiglio Nazionale Delle Ricerche – Istituto Di Chimica Del Riconoscimento Molecolare (CNR-ICRM – Research organization), Dr. Marina Cretich
- HTA Srl (Company), Dr. Giovanni Marchini
- Fondazione INGM (Research organization), Dr. Renata Grifantini
- Politecnico di Milano (Research organization), Prof. Riccardo Bertacco
- Primm Srl (Company), Dr. Angela Pontillo
- ASST Fatebenefratelli Sacco (Research organization), Prof. Maria Rita Gismondo
- Università Degli Studi Di Milano (Research organization), Prof. Martino Bolognesi