BtBs seminar - Nanodynamo quantifies the dynamics of RNA metabolism and unravels extensive coupling between steps of the RNA life cycle

Mattia Pelizzola, Department of Biotechnology and Biosciences, University of Milano‐Bicocca

The coordinated action of transcriptional and post-transcriptional machineries shapes gene expression programs. We developed Nanodynamo, an experimental and computational workflow for quantifying the kinetic rates of nuclear and cytoplasmatic steps of the RNA life cycle. We revealed pervasive post-transcriptional RNA processing. We unraveled coupling between transcriptional, processing, export, decay and translational machineries, which largely contribute to coordinating how cells respond to perturbations that impact gene expression programs

LINK to join the seminar: https://unimib.webex.com/unimib-it/j.php?MTID=m4061398cd4ae89de2ed64044acf51c79

password:  day19 (32919 da telefoni e sistemi video)

The seminar is OPEN to all.

tag:   #BtBsSeminars , #PelizzolaLab_BtBs