SYSBIO – Centre of Systems Biology” is an Italian open access Research Infrastructure (RI), distributed throughout different locations, focused on Systems Biology, the new paradigm for the study of Life Sciences, that integrates molecular analysis, also genome-wide, with math modeling and simulations. It’s funded by Italian Ministry for Research (MIUR), within the Italian roadmap for RI, and operates under an agreement between the National Research Council (CNR) and the University of Milano-Bicocca.
The Director is Prof. Lilia Alberghina, a leader of the European Systems Biology.

SYSBIO tune its Systems Biology approach on mitochondrial metabolism, and its connections with cell growth, cell cycle and cell death, molecular mechanism related to cancer and neurodegeneration.

The project is currently composed by 12 Research Unit (RU), located in Milan and Rome.

Regarding EU, SYSBIO aims to become a qualified hub of ISBE (Infrastructure for Systems Biology – Europe), a large-scale European research infrastructure project on the European Strategy Forum on Research Infrastructures (ESFRI) Roadmap.