Tisi Renata Anita, PhD

Assistant Professor in Molecular Biology

room 5017, building U4, tel. +39 02 6448 3522

lab 5044, building U4, tel. +39 02 6448 3534


The activity is focused on the following research lines
Health research area BtBs UNIMIB

Cancer, Drug Discovery and Pharmacology, Genetic Diseases, Neurodegenerative and neurological diseases, Systems biology

industrial biotechnology research area BtBs UNIMIB
Industrial Biotechnology

Molecular modeling and Structural Biology

Research group

Vertemara Jacopo – PostDoc
room 4064, building U3,  tel. +39 02 6448 3473, jacopo.vertemara@unimib.it

Rizza Fabio – PhD student
room 5017, lab 5044, building U4, tel. +39 02 6448 3522/3534,  f.rizza3@campus.unimib.it

Molteni Cristian – Master student
room 5017, lab 5044/5047, tel. +39 02 6448 3534/3561/3522/3518,  c.molteni14@campus.unimib.it

Homology modelling; Small molecule-protein docking; Protein-protein docking

Research areas

-Signal transduction
-Computational Biology
-Systems Biology
-Biological systems analysis, modelling and simulation

Selected publications

-Bonetti D, Rinaldi C, Vertemara J, et al. (2020) DNA binding modes influence Rap1 activity in the regulation of telomere length and MRX functions at DNA ends. Nucleic Acids Res. 2020;48(5):2424–2441. doi:10.1093/nar/gkz1203

-Gobbini E, Cassani C, Vertemara J, et al. (2018) The MRX complex regulates Exo1 resection activity by altering DNA end structure. EMBO J. 2018;37(16):e98588. doi:10.15252/embj.201798588

-Niedzwiecka K, Tisi R, Penna S, Lichocka M, Plochocka D, Kucharczyk R. Two mutations in mitochondrial ATP6 gene of ATP synthase, related to human cancer, affect ROS, calcium homeostasis and mitochondrial permeability transition in yeast. Biochim Biophys Acta Mol Cell Res. 2018;1865(1):117–131. doi:10.1016/j.bbamcr.2017.10.003

-Palmioli A, Ciaramelli C, Tisi R, et al. Natural Compounds in Cancer Prevention: Effects of Coffee Extracts and Their Main Polyphenolic Component, 5-O-Caffeoylquinic Acid, on Oncogenic Ras Proteins. Chem Asian J. 2017;12(18):2457–2466. doi:10.1002/asia.201700844

last update March 2020